Cardiovascular Side-Effects of Modern Cancer Therapy
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概要
- 論文の詳細を見る
Recent advances in chemotherapy have substantially improved the prognosis of cancer patients. However, many anticancer drugs, especially newly developed `molecular-target drugs, such as the anti-HER2 blocking antibody and the anti-vascular endothelial growth factor antibody, have serious cardiovascular side-effects such as heart failure, thromboembolism, severe hypertension and lethal arrhythmia, which interrupt cancer treatment and decrease the patients quality of life. Despite the increasing clinical significance, cardiologists have not been focusing enough of their attention on this issue. The major cardiovascular complications associated with anticancer drugs, and current diagnosis, treatment and prevention strategies are reviewed. Close collaborations between oncologists and cardiologists is necessary to tackle cardiovascular complications and advance cancer treatment. (Circ J 2010; 74: 1779 - 1786)
- 社団法人 日本循環器学会の論文
- 2010-08-25
著者
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HORIUCHI Hisanori
Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University
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MINAMI Manabu
Department of Radiology, Graduate School of Comprehensive Human Sciences, University of Tsukuba
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Minami Manabu
Department Of Cardiovascular Medicine Graduate School Of Medicine Kyoto University
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MATSUMOTO Shigemi
Department of Translational Clinical Oncology, Graduate School of Medicine, Kyoto University
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Horiuchi Hisanori
Department Of Cardiovascular Medicine Graduate School Of Medicine Kyoto University
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Minami Manabu
Department Of Clinical Innovative Medicine Translational Research Center (m.m.) Outpatient Oncology
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Matsumoto Shigemi
Department Of Clinical Innovative Medicine Translational Research Center (m.m.) Outpatient Oncology
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Horiuchi Hisanori
Department Of Clinical Innovative Medicine Translational Research Center (m.m.) Outpatient Oncology
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