Dynamic study (3D-FSPGR法)の first pass におけるGd-EOB-DTPAとGd-DTPAの大動脈血最大濃度の肝実質に対するコントラスト雑音比に関する基礎的検討

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From the difference of a clinical dose and the molarity of hepatic specificity contrast agent Gadoxetate Sodium (Gd-EOB-DTPA) and Meglumine Gadopentetate (Gd-DTPA), we make one’s own phantom this time, we performed a study of the base about contrast-to-noise ratio (CNR) of the three dimensional-fast spoiled gradient echo (3D-FSPGR) technique and an optimum flip angle (FA) and the bandwidth (BW) for Gd-DTPA dilution 0.3 mmol/l which assumed T1 value of the liver parenchyma of Gd-DTPA dilution 6.0 mmol/l and Gd-EOB-DTPA dilution 1.5 mmol/l which assumed large arterial blood maximum density of first pass in Dynamic study. We assume CNR of FA10˚ in each BW criteria, CNR of Gd-DTPA dilution 6.0 mmol/l becomes the 3.63–4.38 double at the maximum in FA30˚ with each BW; CNR of Gd-EOB-DTPA dilution 1.5mmol/l is with 1.95–2.36 double at the maximum in FA 20–25˚ with each BW. When CNR compares it with a value of FA becoming biggest, with each BW, as for Gd-EOB-DTPA dilution 1.5 mmol/l, about around 40% CNR lowered for Gd-DTPA dilution 6.0 mmol/l. In Dynamic study in Gd-EOB-DTPA, we did not use an imaging condition totally same as Gd-DTPA and understood that we required the setting of the imaging condition that considered the influence of the T1 relaxation time by the difference of a clinic dose and the molarity in first pass.
社団法人　日本放射線技術学会の論文
2009-03-20