^<99m>Tc-MAG_3を用いたガンマカメラ法による分腎クリアランス値算出の精度向上に関する検討

概要

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Both fundamental and clinical studies were performed to improve the precision with which split renal clearance is calculated from the relation between renal clearance and the total renal uptake rate by using ^<99m>Tc-MAG_3, which is mainly excreted into the proximal renal tubules. In the fundamental study, the mostsuitable kidney phantom threshold values for the extracted renal outline were investigated with regard tosize, radioactivity, depth of the kidney phantom, and radioactivity in the background. In the clinical study,suitable timing to obtain additional images for making the ROI and the standard point for calculation ofrenal uptake rate were investigated. The results indicated that, although suitable threshold values were dis-tributed from 25% to 45%, differences in size, solution activity, and the position of the phantom or BG activity did not have significant effects. Comparing 1-3 min with 2-5 min as the time for additional imagesfor ROI, we found that renal areas using the former time showed higher values, and the correlation coefficient of the regression formula improved significantly. Comparison of the timing for the start of data acquisition with the end of the arterial phase as a standard point of calculating renal uptake rate showed improvement in the latter.
社団法人日本放射線技術学会の論文
1999-12-20