Cardiovascular clinical trials in Japan and controversies regarding prospective randomized open-label blinded end-point design
スポンサーリンク
概要
- 論文の詳細を見る
- 2009-02-01
著者
-
Yamazaki Tsutomu
Department of Clinical Epidemiology & Systems, The University of Tokyo
-
Kohro Takahide
Department of Translational Research for Healthcare and Clinical Science, The University of Tokyo
-
Kohro Takahide
Department Of Translational Research For Healthcare And Clinical Science Graduate School Of Medicine
-
Kohro Takahide
Department Of Cardiology Tokyo University School Of Medicine
-
Yamazaki Tsutomu
Department Of Applied Chemistry Tokyo University Of Agriculture And Technology
-
Yamazaki Tsutomu
Department Of Clinical Epidemiology & Systems Graduate School Of Medicine The University Of Toky
-
Yamazaki Tsutomu
Department Of Applied Chemistry Graduate School Of Engineering Tokyo University Of Agriculture And T
関連論文
- Effects of Medication on Cardiovascular Events in the Japanese Coronary Artery Disease (JCAD) Study
- PE-536 The Relationships between BNP and AF in Japanese Patients(PE090,Heart Failure (Biomarker) 2 (M),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society)
- DPE-013 Determinants of Medication and Clinical Outcome in Japanese Atrial Fibrillation Patients under Rate Control Strategy : From Shinken Database 2004-6(DPE03,Atrial/Supraventricular Arrhythmia (Clinical/Treatment) (A),Digital Poster Session (English),
- OE-381 Role of Atrial Fibrillation in Congestive Heart Failure : A Prospective Cohort Study of Shinken Database 2004-6(OE64,Heart Failure (Diagnosis) (M),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- OE-178 Comparison of Age-dependent Mortality between Patients with Cardiovascular Diseases and General Population in Japan(OE30,Preventive Medicine/Epidemiology/Education (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese C
- OE-079 Role of AF in BNP-based Risk Stratification : From an Analysis of Cardiovascular Morbidity in Japanese Patients(OE14,Heart Failure (Biomarker) (M),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- OE-018 Occurrence of Warfarin Discontinuation and Its Determinants in Japanese AF Patients : From a Real-World Analysis(OE03,Thromboembolism/Antithrombotic Therapy/Thrombolysis (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Ja
- OE-015 Effects of Warfarin on Mortality According to CHADS_2 Score and Components in Japanese AF Patients : From Shinken Database 2004-7(OE03,Thromboembolism/Antithrombotic Therapy/Thrombolysis (IHD),Oral Presentation (English),The 73rd Annual Scientific
- FRS-101 The Relationships between Estimated GFR and Prevalence of AF in Japanese Patients(FRS21,New Insights into Chronic Kidney Disease and Renal Circulation (H),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circu
- Japanese Randomized Trial for Investigation of a Combined Therapy of Amiodarone and Implantable Cardioverter Defibrillator in Patients With Ventricular Tachycardia and Fibrillation : The Nippon ICD Plus Pharmacologic Option Necessity (NIPPON) Study Design
- Beta-Blocker Prescription Among Japanese Cardiologists and Its Effect on Various Outcomes
- The Japanese National Health Screening and Intervention Program Aimed at Preventing Worsening of the Metabolic Syndrome
- DPE-013 Determinants of Medication and Clinical Outcome in Japanese Atrial Fibrillation Patients under Rate Control Strategy : From Shinken Database 2004-6(DPE03,Atrial/Supraventricular Arrhythmia (Clinical/Treatment) (A),Digital Poster Session (English),
- OE-178 Comparison of Age-dependent Mortality between Patients with Cardiovascular Diseases and General Population in Japan(OE30,Preventive Medicine/Epidemiology/Education (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese C
- OE-018 Occurrence of Warfarin Discontinuation and Its Determinants in Japanese AF Patients : From a Real-World Analysis(OE03,Thromboembolism/Antithrombotic Therapy/Thrombolysis (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Ja
- OE-015 Effects of Warfarin on Mortality According to CHADS_2 Score and Components in Japanese AF Patients : From Shinken Database 2004-7(OE03,Thromboembolism/Antithrombotic Therapy/Thrombolysis (IHD),Oral Presentation (English),The 73rd Annual Scientific
- FRS-101 The Relationships between Estimated GFR and Prevalence of AF in Japanese Patients(FRS21,New Insights into Chronic Kidney Disease and Renal Circulation (H),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circu
- Body Size and Atrial Fibrillation in Japanese Outpatients
- DPE-013 Determinants of Medication and Clinical Outcome in Japanese Atrial Fibrillation Patients under Rate Control Strategy : From Shinken Database 2004-6(DPE03,Atrial/Supraventricular Arrhythmia (Clinical/Treatment) (A),Digital Poster Session (English),
- Effects of Nicorandil on Cardiovascular Events in Patients With Coronary Artery Disease in The Japanese Coronary Artery Disease (JCAD) Study
- Gender Differences in Patients With Coronary Artery Disease in Japan : The Japanese Coronary Artery Disease Study (The JCAD Study)
- Elevated Serum Uric Acid is an Independent Predictor for Cardiovascular Events in Patients With Severe Coronary Artery Stenosis : Subanalysis of the Japanese Coronary Artery Disease (JCAD) Study
- OJ-160 Comparison of Risk Factors between Angiographically Diffuse versus Focal Stenosis in the Patients Enrolled in Japanese Coronary Artery Disease (JCAD) Study(OJ27,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Oral Presentation
- OE-390 Association between Angiographical Assessment of Luminal Narrowing and Recurrence of Cardiovascular Events : Substudy of Japanese Coronary Artery Disease (JCAD) Study(OE66,Atherosclerosis (Clinical/Pathophysiology) (IHD),Oral Presentation (English)
- FRS-087 The Impact of Diabetes on the Prognosis of Japanese Patients with Coronary Artery Disease(FRS18,New Insights into Metabolic Syndrome (H),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Elevated Serum C-Reactive Protein Levels Predict Cardiovascular Events in the Japanese Coronary Artery Disease (JCAD) Study(Epidemiology)
- Demographics and Changes in Medical/Interventional Treatment of Coronary Artery Disease Patients Over a 3.5-Year Period in Japan : The Japanese Coronary Artery Disease Study: Trend Examination
- Rationale and Design of a Study to Examine Lower Targets for Low-Density Lipoprotein-Cholesterol and Blood Pressure in Coronary Artery Disease Patients : The Japanese Coronary Artery Disease Study II (JCADII)
- OJ-217 Genetic Variations of Mrf-2/Arid5B Confers Risk of Coronary Atherosclerosis in the Japanese Population(Genetics/Genetically engineered models/Gene therapy-2(H/M), The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-482 The Polymorphism in the Adiponectin Gene is Associated with Susceptibility to Coronary Artery Disease(Atherosclerosis, clinical-11 (H) PJ81,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society
- DPE-013 Determinants of Medication and Clinical Outcome in Japanese Atrial Fibrillation Patients under Rate Control Strategy : From Shinken Database 2004-6(DPE03,Atrial/Supraventricular Arrhythmia (Clinical/Treatment) (A),Digital Poster Session (English),
- OE-178 Comparison of Age-dependent Mortality between Patients with Cardiovascular Diseases and General Population in Japan(OE30,Preventive Medicine/Epidemiology/Education (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese C
- OE-018 Occurrence of Warfarin Discontinuation and Its Determinants in Japanese AF Patients : From a Real-World Analysis(OE03,Thromboembolism/Antithrombotic Therapy/Thrombolysis (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Ja
- OE-015 Effects of Warfarin on Mortality According to CHADS_2 Score and Components in Japanese AF Patients : From Shinken Database 2004-7(OE03,Thromboembolism/Antithrombotic Therapy/Thrombolysis (IHD),Oral Presentation (English),The 73rd Annual Scientific
- FRS-101 The Relationships between Estimated GFR and Prevalence of AF in Japanese Patients(FRS21,New Insights into Chronic Kidney Disease and Renal Circulation (H),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circu
- Mechanism of Statin-Induced Myopathy Investigated Using Microarray Technology
- ATP binding Cassette Transporter (ABCA1) variant is one of the determinantsof plasma high density lipoprotein level in Japanese population
- Evidence for association of Ser326Cys polymorphism in 8-oxyguanin DNA glycosylase (OGG1) with susceptibility to coronary heart disease in Japanese
- The Matrix Metalloproteinase-1 (MMP-1) 1G/2G Polymorphism and the Matrix Metalloproteinase-3 (MMP-3) 5A/6A Polymorphism are Useful Genetic Markers for Myocardial Infarction
- Angiotensin II stimulation induces TGF β and its related proteins in cardiac fibroblasts
- Establishment of clinical data management system and its practical application to genetic epidemiology in cardiovascular medicine
- DPE-013 Determinants of Medication and Clinical Outcome in Japanese Atrial Fibrillation Patients under Rate Control Strategy : From Shinken Database 2004-6(DPE03,Atrial/Supraventricular Arrhythmia (Clinical/Treatment) (A),Digital Poster Session (English),
- Cardiovascular clinical trials in Japan and controversies regarding prospective randomized open-label blinded end-point design
- DPE-013 Determinants of Medication and Clinical Outcome in Japanese Atrial Fibrillation Patients under Rate Control Strategy : From Shinken Database 2004-6(DPE03,Atrial/Supraventricular Arrhythmia (Clinical/Treatment) (A),Digital Poster Session (English),
- Development of a Pioneering Clinical Support System Utilizing Information Technology : Clinical Informatics and Genome Analysis
- Genetic Variations of Mrf-2/Arid5b Confer Risk of Coronary Atherosclerosis in the Japanese Population
- DPE-013 Determinants of Medication and Clinical Outcome in Japanese Atrial Fibrillation Patients under Rate Control Strategy : From Shinken Database 2004-6(DPE03,Atrial/Supraventricular Arrhythmia (Clinical/Treatment) (A),Digital Poster Session (English),
- Genetic Analysis in a Patient With Recurrent Cardiac Myxoma and Endocrinopathy
- Beta-Blocker Prescription Among Japanese Cardiologists and Its Effect on Various Outcomes
- Relationship Between Renal Dysfunction and Severity of Coronary Artery Disease in Japanese Patients
- The Significant Association of Genetic Polymorphisms in the KLF5 Gene with Coronary Artery Disease(Atherosclerosis, Clinical 9 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Extensive Oligonucleotide Microarray Transcriptome Analysis of the Rat Cerebral and Arachnoid Tissue
- Serum and cerebrospinal fluid levels of cytokines in acute encephalopathy associated with human herpesvirus-6 infection
- Morning home blood pressure may be a significant marker of nephropathy in Japanese patients with type 2 diabetes : ADVANCED-J study 1
- Superior Benefit of Aggressive Lipid-Lowering Therapy for High-Risk Patients Using Statins : the SUBARU Study : More Hypercholesterolemic Patients Achieve Japan Atherosclerosis Society LDL-C Goals with Rosuvastatin Therapy than with Atorvastatin Therapy
- A Comparison of Differences in the Gene Expression Profiles of Phorbol 12-myristate 13-acetate Differentiated THP-1 Cells and Human Monocyte-derived Macrophage
- Genomic Structure and Mapping of Human Orphan Receptor LXR Alpha : Upregulation of LXRa mRNA During Monocyte to Macrophage Differentiation
- The Gene Expression Profile of Human Umbilical Vein Endothelial Cells Stimulated by Tumor Necrosis Factor α Using DNA Microarray Analysis
- OE-044 Baseline Data of JPPP : The Large Randomized Controlled Trial of Primary Prevention by Enteric Coated Low-dose Aspirin in Japan.(Atherosclerosis, clinical(01)(IHD),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circul
- FRS-102 Event rates of Japanese patients with atherothrombosis : Results from the REduction of Atherothrombosis for Continued Health (REACH) Registry(Clinical Frontiers in Atherosclerosis(IHD),Featured Research Session,The 72nd Annual Scientific Meeting o
- Prevalence, Awareness and Treatment of Cardiovascular Risk Factors in Patients at High Risk of Atherothrombosis in Japan : Results From Domestic Baseline Data of the REduction of Atherotherombosis for Continued Health(REACH) Registry
- PE-379 Lipid-independent Effects of Statins on Cardiovascular Events in the Japanese Coronary Artery Disease Study : Comparison Between Lipophilic and Hydrophilic Statins(Cardiovascular pharmacology, basic/clinical-3, The 71st Annual Scientific Meeting of
- Introduction of a New System for Conducting High-quality Clinical Studies(How to Make Japanese Original Evidence in Cardiology, The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- FRS-011 High-Mobility-Group Protein A2 Associates with the Smad Transcription Factors and Synergistically Promotes Cardiomyocyte Differentiation(Angiogenesis and Regeneration Medicine in Cardiovascular Medicine (M) : FRS3)(Featured Research Session (Engli
- Prognostic Effects of Combined Treatment With Calcium Channel Blockers and Statins in Patients With Coronary Narrowing : From the Japanese Coronary Artery Disease Study
- マイコプラズマにおけるブレイクポイントの考え方
- Bacterial propagation in reusable water reservoirs in a humidified oxygen supply system
- In vitro activity of β-lactams, macrolides, telithromycin, and fluoroquinolones against clinical isolates of Streptococcus pneumoniae : correlation between drug resistance and genetic characteristics
- The Significant Association of the Genetic Polymorphisms of Werner Helicase and β2 Adrenergic Receptor with Susceptibility to Coronary Heart Disease
- Hypertrophic Responses of Cardiomyocytes Induced by Endothelin-1 through the Protein Kinase C-Dependent but Src and Ras-Independent Pathways
- High-Mobility-Group Protein A2 Associates with Smad1, Activates the Csx/Nkx2-5 Gene Expression Cooperatively, and Promotes Cardiomyocyte Differentiation
- Diverse effects of homeobox transcription factor Csx/Nkx2-5 on cardiac myocytes
- IS037 Both Ca^2+/calmodulin-dependent kinase II and calcineurin play critical roles in cardiac hypertrophy
- 5 Establishment of clinical database system and identification of genetic factors contributing to the pathogenesis of atheroscherosis(Symposium 4 (SY4) (IHD) : Molecular Mechanism of Atherosclerosis)(Special Program)
- Proteinases Including MMPs Are Involved in the Pathogenesis of Aortic Aneurysm : A Study of the Transcription Profile with DMA Microarray
- Synthesis of Diamond by DC Plasrna Chemical Vapor Deposition above the Surface of a Water-Ethylene Glycol Solution
- 酸化スズガスセンサ膜の微構造およびホ-ル効果の膜厚依存
- Plasma Cystatin C Concentration Reflects the Severity of Coronary Artery Disease in Patients Without Chronic Kidney Disease
- Eicosapentaenoic Acid (EPA) in Reducing Secondary Cardiovascular Events in Hypercholesterolemic Japanese Patients
- IS029 Role of TNF-α in oxidative stress-induced apoptosis of cardiac myocytes
- Continuous Blockade of L-Type Ca^ Channels Suppresses Activation of Calcineurin nad Development of Cardiac Hypertrophy in Spontaneously Hypertensive Rats
- Statin Treatment for Patients With Paroxysmal Atrial Fibrillation : A J-RHYTHM Substudy
- Reversible Photoswitching Liquid-phase Adsorption on Azobenzene Derivative-grafted Mesoporous Silica
- 1 Development of Quality Indicators in Cardiovascular Medicine(Clinical Quality Management and Clinical Indicators for Patient Care in Cardiovascular Medicine, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Preparation of Hybrid Ordered Inorganic-Organic Mesostructures from an Asymmetrically Bridged Organic Precursor Containing Both Silanolate and Phosphonate
- Screening for Cardiac Dysfunction in Asymptomatic Patients by Measuring B-type Natriuretic Peptide Levels
- ガス中蒸発法による極端に多孔質な酸化スズ膜の作製
- 0099 ANGIOTENSIN II INDUCES PROTEIN KINASE C/RAF-1 KINASE/EXTRACELLULAR SIGNAL-REGULATED PROTEIN KINASE ACTIVATION INDEPENDENT OF SRC AND RAS IN CARDIAC MYOCYTES
- -0297- Isolation of Tyrosine Kinases from Adult Murine Heart(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
- Proposed New Score to Rate the Strength of Evidence and Its Application to Large-Scale Clinical Trials of Angiotensin-Receptor Blockers
- The Present Problems of Prospective Payment System by DPC Based on the Database of 26 University hospitals(Current Problems and Future Impact of the Diagnosis Procedure Combination and Related Payment System in Japan, The 69th Annual Scientific Meeting of
- 2 Present State and Issues of DPC-based Prospective Payment System based on University Hospitals Database(DPC and Clinical Practice of Cardiovascular Medicine, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- 高温X線回折を用いたCuInSe_2生成過程のその場観察
- Intensively Lowering Both Low-Density Lipoprotein Cholesterol and Blood Pressure Does Not Reduce Cardiovascular Risk in Japanese Coronary Artery Disease Patients
- Japanese Guidelines for the Management of Respiratory Infectious Diseases in Children 2007 with focus on pneumonia
- Development and Implementation of an Advanced Coronary Angiography and Intervention Database System
- A Multicenter Study Design to Assess the Clinical Usefulness of Semi-Automatic Measurement of Flow-Mediated Vasodilatation of the Brachial Artery
- Trends in Antidiabetic Prescription Patterns in Japan From 2005 to 2011:Impact of the Introduction of Dipeptidyl Peptidase-4 Inhibitors
- Will Diagnosing Polyvascular Disease in Coronary Heart Disease Patients Improve Their Outcomes?