Separation of microsomal cytochrome b_5 via phase separation in a mixed solution of Triton X-114 and charged dextran

スポンサーリンク

概要

• 論文の詳細を見る
• 1998-04-24

著者

• KAMATAKI Tetsuya

  Laboratory of Drug Metabolism, Graduate School of Pharmaceutical Sciences, Hokkaido University

• 谷 博文

  Division Of Biotechnology And Molecular Chemistry Graduate School Of Engineering Hokkaido University

• Kamidate T

  Hokkaido Univ. Sapporo

• Kamidate Tamio

  Division Of Biotechnology And Molecular Chemistry Graduate School Of Engineering Hokkaido University

• Kamidate Tamio

  Laboratory Of Bioanalytical Chemistry Graduate School Of Engineering Hokkaido University

• Kamataki Tetsuya

  Laboratory Of Drug Metabolism Graduate School Of Pharmaceutical Sciences Hokkaido University

• TANI Hirofumi

  Laboratory of Bioanalytical Chemistry, Graduate School of Engineering, Hokkaido University

• OOURA Takashi

  Laboratory of Bioanalytical Chemistry, Graduate School of Engineering, Hokkaido University

• WATANABE Hiroto

  Laboratory of Bioanalytical Chemistry, Graduate School of Engineering, Hokkaido University

• Ooura Takashi

  Laboratory Of Bioanalytical Chemistry Graduate School Of Engineering Hokkaido University

• Watanabe H

  Kyoto Univ. Kyoto Jpn

• Kamataki Tetsuya

  Laboratory Of Drug Metabolism Division Of Pharmacobio-dynamics Graduate School Of Pharmaceutical Sci

関連論文

• 幽霊
• Application of 4-Iodophenol-enhanced Luminol Chemiluminescence to Direct Detection of Horseradish Peroxidase Encapsulated in Liposomes
• Two Novel Single Nucleotide Polymorphisms (SNPs) of the FMO3 Gene in Japanese
• A Mutation in the Flavin-containing Monooxygenase 3 Gene and its Effects on Catalytic Activity for N-oxidation of Trimethylamine In Vitro
• Overexpression of CYP2A6 in human colorectal tumors
• O-18 Role of Human N-Acetyltransferase in the Metabolic Activation of 2-Phenylbenzotriazole (PBTA) Derivatives.(Proceedings of the 27th Annual Meeting)
• 21C-01-1 Metabolic Activation of PBTA-1 and PBTA-2 by Human Cytochrome P450 1A1.
• Cytochrome P450 gene expression levels in peripheral blood mononuclear cells in comparison with the liver
• Establishment of in silico systems to predict the effects of genetic polymorphism on the enzymatic activity of cytochrome P450
• 金属キレートポリマーを導入したミセル水性二相分配法におけるヒスチジンタグ融合チトクロムb_5及びオリゴペプチドのアフィニティー分配
• Inhibitory Effects of Nicardipine to Cytochrome P450 (CYP) in Human Liver Microsomes(Biopharmacy)
• Co-operative Regulation of the Transcription of Human Dihydrodiol Dehydrogenase(DD)4/Aldo-Keot Reductase(AKR)1C4 Gene by Hepatocyte Nuclear Factor(HNF)-4α/γand HNF-1α.
• Characterization of a Novel Variant (S145C/L311V) of 3α-Hydroxysteroid/Dihydrodiol Dehydrogenase in Human Liver.
• Factor(s) Regulating the Induction of CYP1A1 by Aryl Hydrocarbons in Rabbits
• CHARACTERIZATION OF TRANSGENIC MICE CARRYING A HUMAN FETUS-SPECIFIC CYP3A7.
• "B-9 Factors Regulating CYP1A1 Induction in Adult Rabbit Livers.
• Apparatus for Small-Angle Neutron Scattering and Rheological Measurements under Sheared Conditions
• Inhibiton by EGCG of benzo[a]pyrene-induced mutations in the lung of HITEC mice.
• CYP2A6 gene deletion reduces oral cancer risk in betel quid chewers.(GENERAL SESSION BY ORAL PRESENTATION)(DRUG METABOLISM)
• SUPPRESSION OF PPAR ALPHA SIGNAL CAUSED BY POLYCYCLIC AROMATIC HYDROCARBONS.(GENERAL SESSION BY POSTER PRESENTATION)(MOLECULAR TOXICITY & TOXICOGENOMICS)
• 2B-08 Establishment of Genetically Engineered E.coli Highly Sensitive to Nitrosamines by Introducing Human CYP2E1
• Twenty One Novel Single Nucleotide Polymorphisms (SNPs) of the CYP2A6 Gene in Japanese and Caucasians
• CYP3A5 Contributes Significantly to CYP3A-mediated Drug Oxidations in Liver Microsomes from Japanese Subjects
• In vivo Evaluation of Coumarin and Nicotine as Probe Drugs to Predict the Metabolic Capacity of CYP2A6 Due to Genetic Polymorphism in Thais
• Novel Nonsynonymous Polymorphisms of the CYP1A1 Gene in Japanese
• Toxicological roles of human and rodent CYP2As in the mutagenic activation of N-nitrosamines.(GENERAL SESSION BY ORAL PRESENTATION)(DRUG METABOLISM)
• Novel Mutations of the CYP2A6 Gene in a Thai Population with Lowered Capacity of Coumarin 7-Hydroxylation
• O11-15 Mutagenic activation of tobacco-related N-nitrosamines by rat CYP2As in comparison with human CYP2A6.
• O11-14 Comparison of the toxicolqical roles of mouse CYP2A with human CYP2A6.
• Genetic Polymorphism in the 5'-Flanking Region of Human CYP1A2 Gene : Effect on the CYP1A2 Inducibility in Humans
• Two Novel Haplotypes of CYP2D6 Gene in a Japanese Population
• Eighteen Novel Polymorphisms of the CYP2A13 Gene in Japanesse
• Large-scale Production of Genetically Engineered CYP3A4 in E. coli: Application of a Jarfermenter
• Establishment of Salmonella Tester Strains Co-expressing Cytochrome P450 and NADPH-cytochrome P450 Reductase.
• Application of Genetically Engineered Bacteria Carrying Human Cytochrome P450 to Toxicological Studies
• Metabolic Activation of Dimethylnitrosamine(DMN) by Human CYP2E1 Expressed in O^6-Methylguanine-DNA Methyltransferase-Deficient Cells
• Establishment Of A Salmonella Tester Strain Ultra-Sensitive To Mutagenic Heterocyclic Amines
• DEVELOPMENT OF PRACTICAL METHODS WHICH MIMIC DRUG METABOLISM IN HUMANS.
• EXPRESSION OF RECOMBINANT HUMAN CYTOCHROME P450 (P450 OR CYP) 2A6 IN ESCHERICHIA COLI.
• "S2-3 STRATEGIC PROPOSALS TO AVOID TOXIC DRUG INTERACTIONS DURING NEW DRUG DEVELOPMENT : MOLECULAR TOXICOLOGY PROPOSALS (Strategy how we can learn drug-drug interaction during the development of a new drug)
• Stable expression of CYP3A4 and CYP3A7, adult and fetal-specific forms of cytochrome P450 in human liver, in CHL cells and its application to toxicological testing.
• Effects of NO-1886 (Ibrolipim), a Lipoprotein Lipase-Promoting Agent, on Gene Induction of Cytochrome P450s, Carboxylesterases, and Sulfotransferases in Primary Cultures of Human Hepatocytes
• Detection of Three Genetic Polymorphisms in the 5'-Flanking Region and Intron 1 of Human CYP1A2 in the Japanese Population
• Homologous Unequal Cross-Over within the Human CYP2A Gene Cluster as a Mechanism for the Deletion of the Entire CYP2A6 Gene Associated with the Poor Metabolizer Phenotype
• P-50 3次元微小流体ネットワークを用いた変異原物質のオンチップ生物発光レポーターアッセイ(ポスター(1))
• O-13 3次元微小流体ネットワークを用いた変異原物質のオンチップ生物発光レポーターアッセイ(一般演題:口演(2)-DNA損傷・抗変異原・小核・試験法の開発-)
• リポソームに内封したペルオキシダーゼを触媒に用いるフルオレセイン化学発光による過酸化水素の定量(ナノ空間と分析化学)
• 変異原物質のオンチップバイオアッセイ
• Triton X-114を用いるミセル水性二相分配法による膜タンパク質の抽出に及ぼす荷電水溶性ポリマーの添加効果
• Selective Uptake of Copper(II)and Zinc(II)Ions Using Liposomes without Ionophores
• Association of CYP2A6 Gene Deletion with Cigarette Smoking Status in Japanese Adults
• Preconcentration of Catecholamines into Liposomes with Imposed pH Gradients
• Studies on the Interactions between Drug and Estrogen. II. On the Inhibitory Effect of 29 Drugs Reported to Induce Gynecomastia on the Oxidation of Estradiol at C-2 or C-17
• Rheo-SANS Study of an Aqueous Suspension of Poly(Methyl Methacrylate-co-Styrene) Particle
• ペルオキシダ-ゼを触媒とするアゾ色素の退色反応における活性化剤
• Production of Inhibitory Polyclonal Antibodies against Cytochrome P450s
• Separation of microsomal cytochrome b_5 via phase separation in a mixed solution of Triton X-114 and charged dextran
• Selective Solubilization of Microsomal Electron-Transfer Proteins with Alkylglucoside
• 21WA-04-2 Regulation of NAD(P)H: quinone oxidoreductase_1 (NQO_1) Gene Expression in Guinea Pig.
• Equilibrium Study on Interactions between Proteins and Bile-Salt Micelles by Micellar Electrokinetic Chromatography
• Metabolism of Selegiline Hydrochloride, a Selective Monoamine B-type Inhibitor, in Human Liver Microsomes
• RECENT PROGRESS OF THE TOKYO-ELECTRON BEAM ION TRAP
• The Electron-Beam Ion Trap Experimental Program
• Direct Determination of Horseradish Peroxidase Encapsulated in Liposomes by Using Luminol Chemiluminescence
• Determination of Peroxidase Encapsulated in Liposomes Using Homogentisic Acid γ-Lactone Chemiluminescence
• Cationic Liposomes Enhanced Firefly Bioluminescent Assay of Bacterial ATP in the Presence of an ATP Extractant
• Direct Detection of Horseradish Peroxidase as a Marker Molecule Encapsulated in Liposomes via Use of Fluorescein Chemiluminescence
• Uptake of Transition Metal Ions Using Liposomes Containing Dicetylphosphate as a Ligand
• Application of Horseradish Peroxidase-Encapsulated Liposomes as Labels for Immunodotblotting
• Enhancement of Firefly Bioluminescence Using Liposomes Containing Cationic Components
• Aqueous Micellar Two-Phase Systems for Protein Separation
• Extraction of Proteins Based on Phase Separation in Aqueous Triblock Copolymer Surfactant Solutions
• Characterization of Horseradish Peroxidase-Encapsulated Liposomes Prepared by an Extrusion Technique
• Determination of Peroxidase with a Chemiluminescence Reaction of Homogentisic Acid γ-Lactone in Non-Aqueous Media
• Chemiluminescent Determination of Peroxidase with Purpurogallin Carboxylic Acid
• Time-Resolved Luminol Chemiluminescence for Simultaneous Determination of Cobalt(II) and Copper(II)
• 光るとわかる? : 化学発光・生物発光分析法の現状
• Association of CYP2A6 Gene Deletion with Cigarette Smoking Status in Japanese Adults
• Tracer Diffusion of a Ligand-Stabilized Two-Shell Gold Cluster
• Peroxyoxalate Chemi luminescent Assay of Ascorbic Acid Based on Autoxidation with Oxygen in Reversed Micelle
• Fluorescein Chemiluminescence-Delay Method for the Determination of Ultratrance Amounts of Copper(II)
• A Major Genotype in UDP-glucuronosyltransferase 2B15
• Genetically Engineered Bacterial Cells Co-expressing Human Cytochrome P450 with NADPH-cytochrome P450 Reductase : Prediction of Metabolism and Toxicity of Drugs in Humans
• Cell-specific transcriptional regulation of the human CYP1B1 (DRUG METABOLISM) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
• 微小流体デバイスを用いたイムノアッセイ
• ミセル水生二相分配法を用いた膜タンパク質の抽出分離
• Effects of Spatial Confinement on Dielectric Relaxation of Block Copolymers having Tail, Loop, and Bridge Conformations
• Synthesis and Linear Viscoelasticity of Model Comb Polymers
• 8-225 アジア人財資金構想・北大フロンティアプログラムにおける産学連携専門教育((20)産学連携教育-III,口頭発表論文)
• マイクロチップ液体クロマトグラフィーのためのオンチップ電気化学フローセルの開発
• Lung tumorigenesis promoted by anti-apoptotic effects of cotinine, a nicotine metabolite through activation of PI3K/Akt pathway

もっと見る 閉じる

スポンサーリンク