Effect of Renin-Angiotensin-Aldosterone System Triple Blockade on Non-Diabetic Renal Disease : Addition of an Aldosterone Blocker, Spironolactone, to Combination Treatment with an Angiotensin-Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker
スポンサーリンク
概要
- 論文の詳細を見る
- 2008-01-01
著者
-
Tabara Yasuharu
国立循環器病センター研究所 疫学部
-
Tsubakihara Yoshiharu
Department Of Kidney Disease And Hypertension Osaka General Medical Center
-
Tsubakihara Yoshiharu
Department Of Nephrology Osaka Prefectural Hospital
-
Tsubakihara Yoshiharu
Department Of Internal Medicine Division Of Nephrology And Rheumatology Aichi Medical University Sch
-
Tsubakimoto Yoshinori
Department Of Cardiolgy Kyoto Prefectural University Of Medicine
-
IMAI Enyu
Department of Nephrology, Osaka University Graduate School of Medicine
-
Imai E
Department Of Nephrology Osaka University Graduate School Of Medicine
-
Imai Enyu
大阪大学 医学系研究科保健学専攻検査情報学研究室
-
Imai Enyu
大阪大学 医系研究病態情報内科学腎臓研究室
-
Imai Enyu
琉球大学医学部附属病院 血液浄化療法部
-
Imai Enyu
大阪府立病院機構大阪府立急性期総合医療センター 腎臓･高血圧内科
-
Imai Enyu
Department Of Nephrology Osaka University Graduate School Of Medicine
-
NAGASAWA Yasuyuki
Department of Nephrology, Osaka University Graduate School of Medicine
-
MIKAMI Satoshi
Department of Nephrology, Osaka University Graduate School of Medicine
-
FURUMATSU Yoshiyuki
Department of Kidney Disease and Hypertension, Osaka General Medical Center
-
TOMIDA Kodo
Department of Kidney Disease and Hypertension, Osaka General Medical Center
-
KANEKO Tetsuya
Department of Kidney Disease and Hypertension, Osaka General Medical Center
-
OKADA Noriyuki
Department of Kidney Disease and Hypertension, Osaka General Medical Center
-
SHOJI Tatsuya
Department of Kidney Disease and Hypertension, Osaka General Medical Center
-
Nagasawa Y
Department Of Nephrology Osaka University Graduate School Of Medicine
-
Nagasawa Yasuyuki
大阪大学 医学系研究科内科学講座腎臓内科
-
Nagasawa Yasuyuki
Osaka Univ. Graduate School Of Medicine Osaka Jpn
-
Shoji Tatsuya
Department Of Kidney Disease And Hypertension Osaka General Medical Center
-
Furumatsu Yoshiyuki
Department Of Kidney Disease And Hypertension Osaka General Medical Center
-
Mikami Satoshi
Department Of Kidney Disease And Hypertension Osaka General Medical Center
-
Tomida Kodo
Department Of Kidney Disease And Hypertension Osaka General Medical Center
-
Kitahara Tatsuro
Department Of Cardiology Pulmonology And Nephrology Yamagata University School Of Medicine
-
Kitahara Tatsuro
山形大学 医学部循環･呼吸･腎臓内科学
-
Imai Enyu
大阪大学 医学系研究科老年･腎臓内科学
-
Tarutani Yasuhiro
Division Of Cardiology Department Of Medicine Kohka Public Hospital
-
Nagasawa Yasuyuki
大阪府立病院機構大阪府立急性期総合医療センター 腎臓･高血圧内科
-
Nagasawa Yasuyuki
Department Of Nephrology Osaka University Graduate School Of Medicine
-
Imai Enyu
Department Of Internal Medicine And Therapeutics Osaka University Graduate School Of Medicine
-
Imai E
Tohoku Univ. Graduate School Of Medicine Sendai
-
Okada Noriyuki
Department Of Kidney Disease And Hypertension Osaka General Medical Center
-
Mikami Satoshi
Department Of Pure And Applied Chemistry Faculty Of Science And Technology Tokyo University Of Scien
-
Kaneko Tetsuya
Third Department Of Internal Medicine Division Of Nephrology Hypertension Endocrinology And Diabetol
-
Tamura Kouichi
Second Department Of Internal Medecine Yokohama City University School Of Medicine
-
Kato T
Department Of Neurology Hematology Metabolism Endocrinology And Diabetes Yamagata University School
-
Shoji Tatsuya
Department Of Electrical And Communication Engineering Graduate School Of Engineering Tohoku Univers
-
TAKADA YASUHARU
Saijo Central Hospital
-
Kobayashi Toru
Center for Adult Diseases
-
Takahashi Kazuei
First Department Of Internal Medicine And Division Of Radiology Yamagata University School Of Medici
-
Kaneko Tetsuya
Department Of Environmental Health Faculty Of Health Sciences Kyorin University
-
Syoji Tatsuya
Department Of Nephrology Osaka Prefectural Hospital
-
Konta Tsuneo
First Department Of Medicine Yamagata University
-
Tsukamoto Yusuke
Division Of Nephrology Department Of Internal Medicine Juntendo University School Of Medicine
-
Kobayashi Tatsuya
First Department Of Medicine Yamagata University
-
Konta Tsuneo
Department Of Neurology Hematology Metabolism Endocrinology And Diabetes Yamagata University School
-
Kato Takeo
Department Of Neurology Hematology Metabolism Endocrinology And Diabetes Yamagata University School
-
Kaneko Tetsuya
Department of Applied Physics and Chemistry, The University of Electro-Communications, Chofu, Tokyo 182-8585
-
IMAI Enyu
Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine
-
TSUBAKIHARA Yoshiharu
Department of Comprehensive Kidney Disease Research, Osaka University Graduate School of Medicine
関連論文
- Association of the Functional Variant in the 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Gene With Low-Density Lipoprotein-Cholesterol in Japanese
- Loss of ACE2 accelerates time-dependent glomerular and tubulointerstitial damage in streptozotocin-induced diabetic mice
- The Japanese Society of Hypertension Committee for Guidelines for the Management of Hypertension
- Accumulation of common polymorphisms is associated with development of hypertension : a 12-year follow-up from the Ohasama study
- Association of SLC6A9 Gene Variants with Human Essential Hypertension
- Fas promoter region gene polymorphism is associated with an increased risk for myocardial infarction
- Asymptomatic Cerebral Microbleeds Seen in Healthy Subjects Have a Strong Association With Asymptomatic Lacunar Infarction(Stroke)
- PJ-713 Seasonal Mortality Variation in Out-of-hospital Cardiac Arrest : Analysis from AMI-Kyoto Multi-Center Risk Study Database(PJ120,Cardiopulmonary and Critical Care/ACLS (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese
- OJ-058 Bone Marrow AT1 Receptor Augments Neointima Formation by Promoting Mobilization of Smooth Muscle Progenitor Cells in a Platelet-Derived SDF-1α-Dependent Manner(OJ10,Atherosclerosis, Basic (IHD),Oral Presentation (Japanese),The 73rd Annual Scientifi
- OE-232 Bone Marrow Angiotensin AT1 Receptor Regulates Differentiation of Monocyte/Macrophage-Lineage Progenitors from Hematopoietic Stem Cells(OE40,Atherosclerosis, Basic 2 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japane
- FRS-066 When and How should We Use Central BP in Clinical Hypertension? : Report from ABC-J Study(FRS14,New Aspects for Hypertension (H),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-616 Mild Renal Dysfunction Accelerated Atherosclerotic Development by Augmenting Mobilization of Bone Marrow Monocyte-lineage progenitors from Bone Marrow via CCR2-Mediated Signals(Atherosclerosis, basic(08)(IHD),Poster Session(Japanese),The 72nd Annua
- PJ-376 Bone Marrow AT1 and AT2 Differentially Modulate Vascular Repair by Regulating Mobilization of Bone Marrow-derived c-Kit^-Sca-1^+Lin^- Progenitors via SDF-1 α/CXCR4 Axis(Restenosis basic/clinical(04)(IHD),Poster Session(Japanese),The 72nd Annual Sci
- OE-416 Novel Action of Angiotensin AT1 Receptor on Bone Marrow Stem Cells, Promotion of Monocyte/Macrophage Lineage Differentiation from Hematopoietic Stem Cells.(Atherosclerosis, clinical(02)(IHD),Oral Presentation(English),The 72nd Annual Scientific Mee
- OE-145 Multi-center Cross-sectional Study to Characterize Antihypertensive Treatments in terms of Central Blood Pressure Evaluated by Radial Artery Pulse Waveform(Hypertension, clinical(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting
- OE-071 A Genom-Wide Association Study of SNPs in the risk of Atherosclerosis Obliterans(Heart failure, clinical(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- An Association between Decreased Estimated Glomerular Filtration Rate and Arterial Stiffness
- An Association between Metabolic Syndrome and the Estimated Glomerular Filtration Rate
- DPJ-013 Hepatocyte Growth Factor Attenuates TGF-β1 Angiotensin II Crosstalk by Down Regulation of Angiotensin II Type 1 Receptor through PTEN/Akt Pathway(DPJ03,Kidney/Renal Circulation/CKD (H),Digital Poster Session (Japanese),The 73rd Annual Scientific M
- Clinical Practice Guidebook for Diagnosis and Treatment of Chronic Kidney Disease
- Prevalence of chronic kidney disease (CKD) in the Japanese general population predicted by the MDRD equation modified by a Japanese coefficient
- Report of the Asian Forum of Chronic Kidney Disease Initiative (AFCKDI) 2007. "Current status and perspective of CKD in Asia" : diversity and specificity among Asian countries
- Effect of Renin-Angiotensin-Aldosterone System Triple Blockade on Non-Diabetic Renal Disease : Addition of an Aldosterone Blocker, Spironolactone, to Combination Treatment with an Angiotensin-Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker
- Abnormal nocturnal blood pressure profile is associated with mild cognitive impairment in the elderly : the J-SHIPP study
- Serum Gamma-Glutamyl Transferase Levels are Associated with Metabolic Syndrome in Community-Dwelling Individuals
- Association of monocyte chemoattractant protein 1 gene polymorphism with susceptibility to nonfamilial idiopathic dilated cardiomyopathy
- Alcohol Consumption Is Associated with Decreased Insulin Resistance Independent of Body Mass Index in Japanese Community-Dwelling Men
- Silent cerebral microbleeds associated with arterial stiffness in an apparently healthy subject
- FRS-068 Class Differences in the Effects of BP-lowering Drugs on Central Blood Pressure : The J-SHIPP Study(FRS14,New Aspects for Hypertension (H),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- High Prevalence of Prehypertension Is Associated with the Increased Body Mass Index in Community-Dwelling Japanese
- Association between Serum Gamma-Glutamyl Transferase Level and Prehypertension among Community-Dwelling Men
- Renal pathology of ANCA-related vasculitis : proposal for standardization of pathological diagnosis in Japan
- An Association between Body Mass Index and Estimated Glomerular Filtration Rate
- Effects of Obesity and Smoking on Mental Stress-Induced Blood Pressure and Augmentation Index Responses in Normotensive Young Males : The J-SHIPP Study
- PJ-431 Silent cerebral microbleeds : prevalence and associations with carotid arterial parameters in comparison with lacunar infarction and leukoaraiosis(Cerebrovascular circulation/Stroke(02)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting
- Guidelines for Diagnosis and Treatment of Patients With Vasospastic Angina (Coronary Spastic Angina) (JCS 2008) : Digest Version
- OJ-014 Spotty Calcification Pattern of Culprit Coronary Artery Plaque is Associated with Lipid-rich Characteristics on IB-IVUS(OJ03,Intravascular Imagings (I),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Soci
- OE-094 The Effects of Pioglitazone on Postprandial Central Blood Pressure Regulation in Patients with Type 2 Diabetes Mellitus(OE16,Diabetes (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Comparison of Arterial Functional Evaluations as a Predictor of Cardiovascular Events in Hypertensive Patients : The Non-Invasive Atherosclerotic Evaluation in Hypertension (NOAH) Study
- PE-310 Impaired Postprandial Vasodilatation in Metabolic Syndrome. On behalf of MEAL Investigators.(Diabetes/Obesity/Metabolic syndrome(06)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PE-121 Assessment of Relationship Between Calcification Pattern and Plaque Characteristics in Patients With Acute Coronary Syndrome : On Behalf of ATHLETE Investigators(Acute coronary syndrome, basic/clinical(03)(IHD),Poster Session(English),The 72nd Annu
- Whole-Body Periodic Acceleration Enhances Brachial Endothelial Function
- Renal Protective Effect in Hypertensive Patients : The High Doses of Angiotensin II Receptor Blocker (HARB) Study
- Renal-Protective Effect of T- and L-Type Calcium Channel Blockers in Hypertensive Patients : An Amlodipine-to-Benidipine Changeover (ABC) Study
- PJ-457 Chronic Effects of Angiotensin II Receptor Blockade on Coronary Fibrinolytic Function in Patients with Coronary Artery Disease(Coronary circulation, basic/clinical-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-453 Effects of Chronic Smoking on Coronary Fibrinolytic Function in Women with Normal Coronary Arteries(Coronary circulation, basic/clinical-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-228 Possibility of Adenosine Triphosphate Stress 3D-Echocardiography in Diagnosis of Ischemic Heart Disease(Echo/Doppler-10, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Relationship between Metabolic Syndrome and Trp64Arg Polymorphism of the β3-Adrenergic Receptor Gene in a General Sample : The Shigaraki Study
- The Association between Morning Hypertension and Metabolic Syndrome in Hypertensive Patients
- Impact of Paraoxonase Polymorphism (Q192R) on Endothelial Function in Intact Coronary Circulation
- PJ-772 The Present Condition of the Morning Hypertension Patients after JSH2004(Hypertension, clinical-12 (H) PJ134,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-689 Relationship between a Metabolic Syndrome and the Polymorphism of the Beta3 Adrenergic Receptor Gene in a General Sample (S-town study)(Diabetes/Obesity/Metabolic syndrome-13 (H) PJ116,Poster Session (Japanese),The 70th Anniversary Annual Scientifi
- PJ-388 The Impact of Whole-body, Periodic Acceleration on Vascular Endothelial Function and Nitric Oxide Release(Exercise test/Cardiac rehabilitation-3 (IHD) PJ66,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Cir
- PJ-010 Aortic Stiffening Precedes Coronary Endothelial Dysfunction in Type II Diabetes Mellitus(Coronary circulation, basic/clinical-4 (IHD) PJ2,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- High blood pressure worsens age-related increases in arterial stiffness evaluated by pulse wave velocity in subjects with lifestyle-related diseases
- Fas Ligand mRNA Levels of Circulating Leukocytes Reflect Endothelial Dysfunction in Hyperlipidemic but Not in Non-Hyperlipidemic Patients
- PJ-032 Fas Ligand Expression Levels in Mononuclear Cells May Indicate the Degree of Improvement of Endothelial Function by Statin(Endothelium-5 (H) PJ6,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation So
- Fas Ligand mRNA Levels of Peripheral Blood Mononuclear Cells may be a Novel Clinical Marker in Patients with Hyperlipidemia (Atherosclerosis, Clinical 10 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Combined Analysis of Polymorphisms in Angiotensinogen and Adducin Genes and Their Effects on Hypertension in a Japanese Sample : The Shigaraki Study
- Evaluation of Morning Blood Pressure Elevation and Autonomic Nervous Activity in Hypertensive Patients Using Wavelet Transform of Heart Rate Variability
- ACE2 Mutant Mice Increase Cardiac Angiotensin II and Increase Incidence of Heart Failure in Response to Pressure Overload (Heart Failure, Basic 7 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Influence of meal intake on pulse wave indices in type 2 diabetes
- Associations of Obesity Measures With Metabolic Risk Factors in a Community-Based Population in Japan
- PE-167 The Relationship between Alcohol Intake and Coronary Calcification in Middle-aged Healthy Japaense Men(Atherosclerosis, clinical-7 (H) PE28,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- FRS-082 Features and Preliminary Results of the Multicenter Registry of the Coronary Spasm Association(FRS17,Novel Approaches to Treatment of CAD (IHD),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Soci
- PJ-042 Pivotal Roles of CYLD (cylindromatosis) as a Deubiquitinating Enzyme in Vasculature(Atherosclerosis, basic(05)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-131 Bone Marrow AT1 and AT2 Modulate Vascular Repair by Regulating Mobilization and Differentiation of Vascular Progenitor Cells and Macrophage Activation(Restenosis basic/clinical-3, The 71st Annual Scientific Meeting of the Japanese Circulation Socie
- PJ-072 Angiotensin II Receptor Blocker Stabilizes Vulnerable Plaque and Reduces Susceptibility of Plaque Rupture in Apolipoprotein E Deficient Mice(Atherosclerosis, basic-8, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-068 A Wire-Induced Arterial Injury Accelerated the Destabilization of Remote Established Atherosclerotic Plaques in ApoE-deficient Mice(Atherosclerosis, basic-8, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-034 Bone Marrow AT1 Accelerated the Development of Atherosclerosis by Regulating Differentiation of Macrophage Progenitors and Macrophage Functions(Atherosclerosis, basic-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Identification of Hypertension-Susceptibility Genes and Pathways by a Systemic Multiple Candidate Gene Approach : The Millennium Genome Project for Hypertension
- Effect of Acute and Long-Term Aerobic Exercise on Arterial Stiffness in the Elderly
- PJ-145 Periostin as a Novel Therapeutic Target for Heart Failure(Acute coronary syndrome, basic/clinical-7, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-062 Zyxin Progresses Epithelial-Mesenchymal Transition under the Control of Twist1 and Contributes to Endocardial Morphogenesis(PE011,Congenital Heart Disease (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation S
- PJ-740 Hepatocyte Growth Factor (HGF), but not Vascular Endothelial Growth Factor (VEGF), Attenuated Ang II-induced EC Senescence by Inhibiting PIP3/rac1 Activity(PJ124,Peripheral Cirulation/Vascular Disease (Therapy) 4 (H),Poster Session (Japanese),The 7
- OJ-060 Hepatocyte Growth Factor Attenuate Ang II-induced Inflammation and Proliferation of Smooth Muscle Cell through EGF Receptor Degradation(OJ10,Atherosclerosis, Basic (IHD),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanes
- PJ-686 Hepatocyte Growth Factor Can Attenuate Senescense of EPC through Anti-oxidative Stress Effect(Peripheral circulation/Vascular disease-6, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- 3 Functional Analysis of Novel Antimicrobial Peptide, AG (Angiogenic Peptide)-30, with Angiongenic Property, toward Clinical Application(The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OE-040 FHL-2 Expresses in Endothelial Cell and Suppresses VEGF-induced Angiogenesis Via Sphingosine Kinase-1(Arrhythmia, diagnosis/Pathophysiology/EPS(01)(A),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society
- OJ-195 Pivotal Roles of Deubiquitinating Enzymes UCHL1, HAUSP, and CYLD in Vasculature as an Anti-proliferative and Anti-inflammatory Effect(Atherosclerosis, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-345 Hepatocyte Growth Factor Attenuates Angiotensin II Induced Renal Fibrosis through TGF-B Suppression by Anoikis of Myofibroblasts(Kidney/Renal circulation(06)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation
- OJ-125 HGF,but not VEGF, Attenuated Angiotensin II-induced Senescence in EPC through Anti-Oxidative Stress Effect by Inhibiting Rac1 Activation.(Regeneration(angiogenesis / myocardial regeneration)(02)(M),Oral Presentation (Japanese),The 72nd Annual Scien
- PJ-762 Requirement of HIF-1a Signaling on the Expression of Nkx2.5 for Normal Heart Developement in Xenopus(Development and differentiation-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-098 Ubiquitin C-terminal Hydroxylase L1 (UCHL1), the Causative Genes of Inherited Parkinson's Disease, Has an Anti-inflammatory Action in Endothelial Cells(Molecular biology, vascular-3 (H) PJ17,Poster Session (Japanese),The 70th Anniversary Annual Sci
- Migraine Is Associated with Enhanced Arterial Stiffness
- A Case of Primary Aldosteronism Associated with Renal Artery Stenosis and Preclinical Cushing's Syndrome
- A Genome-Wide Association Study of Hypertension-Related Phenotypes in a Japanese Population
- evidence-based practice guideline for the treatment of chronic kidney disease
- Maintaining high hemoglobin levels improved the left ventricular mass index and quality of life scores in pre-dialysis Japanese chronic kidney disease patients
- Tonsillectomy and steroid pulse (TSP) therapy for patients with IgA nephropathy : a nationwide survey of TSP therapy in Japan and an analysis of the predictive factors for resistance to TSP therapy
- A nationwide survey of rapidly progressive glomerulonephritis in Japan : etiology, prognosis and treatment diversity
- Design and methods of a strategic outcome study for chronic kidney disease : Frontier of Renal Outcome Modifications in Japan
- Quadriceps sarcopenia and visceral obesity are risk factors for postural instability in the middle-aged to elderly population
- Associations between short one-leg standing time and speed of sound of calcaneal bone in a general population : The Shimanami Health Promoting Program (J-SHIPP) study
- Clinicoepidemiological manifestations of RPGN and ANCA-associated vasculitides : an 11-year retrospective hospital-based study in Japan
- The counterregulating role of ACE2 and ACE2-mediated angiotensin 1-7 signaling against angiotensin II stimulation in vascular cells
- Strong suppression of the renin-angiotensin system has a renal-protective effect in hypertensive patients : High-dose ARB with ACE inhibitor (Hawaii) study
- Blood Pressure Is the Main Determinant of the Reflection Wave in Patients with Type 2 Diabetes
- An Association of 5, 10-Methylenetetrahydrofolate Reductase (MTHFR) Gene Polymorphism and Ischemic Stroke
- Lipocalin-Type Prostaglandin D Synthase Is Associated With Coronary Vasospasm and Vasomotor Reactivity in Response to Acetylcholine