Total Phenolic Content, Antioxidative, Anti-amylase, Anti-glucosidase, and Antihistamine Release Activities of Bangladeshi Fruits

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概要

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• To seek out a cheap source of dietary polyphenols and antioxidants along with anti-amylase and anti-glucosidase activities, ethanol extracts of eleven cheap Bangladeshi fruits were investigated. The extracts were also examined for anti-allergic activity using rat peritoneal exudate cells exposed to the calcium ionophore A23187. Phyllanthus emblica (emblic myrobalan) had the highest total polyphenol content (339 mg gallic acid equivalent (GAE)/g), followed by Syzygium cumini (Indian blackberry; 192.3 mg GAE/g), and Aegle marmelos (wood apple; 53.7 mg GAE/g). P. emblica, and S. cumini also exhibited the most potent DPPH radical scavenging activity, with an IC50 of 2.1 and 8.6 μg/mL respectively. These extracts also showed promising reducing powers with P. emblica having the greatest such activity (optical density (O.D.) 1.66), followed by S. cumini (O.D. 1.34), at a concentration of 0.2 mg/mL. The extracts of Artocarpus heterophyllus (jackfruit) and S. cumini showed promising chelating activities. At a concentration of 1 mg/mL, Dillenia indica (chalta) showed the highest inhibition of α-amylase activity (60%), and A. marmelos, D. indica, P. emblica, Spondias dulcis (hog-plum) & S. cumini completely inhibited α-glucosidase activity (100%). Apart from A. heterophyllus, D. indica and Phyllanthus acidus (star-gooseberry), all other extracts inhibited the release of histamine from the peritoneal exudate cells, with S. cumini having the strongest effect. These fruits therefore have activities beneficial to physiological health.

• 2008-05-01

著者

• TAKASUGI Mikako

  Department of Human Nutrition, Faculty of Human Life Science, Yamaguchi Prefectural University

• Takasugi Mikako

  Department Of Applied Chemistry And Biochemistry Faculty Of Engineering Kyushu Sangyo University

• Aoshima Hitoshi

  Yamaguchi Univ. Yamaguchi Jpn

• Aoshima Hitoshi

  Applied Molecular Bioscience Graduate School Of Medicine Yamaguchi University

• Biswas Rajat

  Biotechnology And Genetic Engineering Discipline Khulna University

• HOSSAIN Sheikh

  Applied Molecular Bioscience, Graduate School of Medicine, Yamaguchi University

• TSUJIYAMA Iyo

  Applied Molecular Bioscience, Graduate School of Medicine, Yamaguchi University

• ISLAM Md.

  Biotechnology and Genetic Engineering Discipline, Khulna University

• Hossain Sheikh

  Khulna Univ. Khulna Bgd

• Tsujiyama Iyo

  Applied Molecular Bioscience Graduate School Of Medicine Yamaguchi University

• Islam Md.

  Biotechnology And Genetic Engineering Discipline Khulna University

関連論文

• Total Phenolic Content, Antioxidative, Anti-amylase, Anti-glucosidase, and Antihistamine Release Activities of Bangladeshi Fruits
• Potentiation of the Response of GABA_A Receptors by Bangladeshi Medicinal Plants
• Characterization of Trans Eicosapentaenoic Acid Isomers: Oxidative Stability and Anti-Inflammatory Activity
• Total phenolic content, antioxidative, anti-amylase, anti-glucosidase, and antihistamine release activities of Bangladeshi fruits

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