Construction of Novel High Throughput Recognition Systems Using Labeled Peptide Arrays Focusing on Protein Detection Chips

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概要

• 論文の詳細を見る
• 2007-03-01

著者

• Mihara H

  Nagasaki Univ. Nagasaki

• Mihara H

  Department Of Bioengineering Tokyo Institute Of Technology

• Mihara H

  Graduate School Of Bioscience And Biotechnology Tokyo Institute Of Technology

• Mihara H

  Tokyo Inst. Technol.

• Mihara Hisakazu

  Tokyo Inst. Technol. Yokohama Jpn

• MIHARA Hisakazu

  Department of Bioengineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Te

• USUI Kenji

  Department of cardiology Surugadai Nihon Univ.Hospital

• NOKIHARA Kiyoshi

  Hipep Laboratories Inc.

• OHYAMA Takafumi

  HiPep Laboratories

• KAWAKAMI Hirochika

  HiPep Laboratories

• KAWAHIRA Noboru

  HiPep Laboratories

• KODAMA Yukiko

  HiPep Laboratories

• MIYAZATO Naeko

  HiPep Laboratories

• ONO Noriko

  HiPep Laboratories

• RASIDI Sven

  HiPep Laboratories

• OKA Yasuo

  Nippon light Metal Company, Ltd.

• Usui Kenji

  Department Of Bioengineering Tokyo Institute Of Technology

• Usui K

  Laboratory Of Insect Toxicology The Institute Of Physical And Chemical Research

• Mihara Hisakazu

  Department Of Applied Chemistry Faculty Of Engineering Nagasaki University

• Mihara Hisakazu

  Department Of Bioengineering Graduate School Of Bioscience And Biotechnology Tokyo Institute Of Tech

• Mihara Hisakazu

  Department Of Bioengineering Faculty Of Bioscience And Biotecnology Tokyo Institute Of Technology

• Mihara Hisakazu

  Graduate School Of Bioscience And Biotechnology Tokyo Institute Of Technology

• Oka Yasuo

  Nippon Light Metal Company Ltd.

• Usui Kenji

  Tokyo Inst. Technol. Yokohama Jpn

• Mihara H

  Faculty Of Engineering Kyushu Institute Of Technology

• Usui K

  Department Of Bioengineering Tokyo Institute Of Technology

• Uchiumi Kyoichi

  Insect Toxicology And Physiology The Lnstitute Of Physical And Chemical Research (rlken)

• Mihara Hisakazu

  Department Of Bioengineering Graduate School Of Bioscience And Biotechnology Tokyo Institute Of Tech

• Nokihara K

  Hipep Laboratories

• Nokihara Kiyoshi

  Hipep Laboratories

関連論文

• The Standard CD Spectrum for 3_ Helix of Peptides
• Conformation of Hexane-soluble Depsipeptides
• In Vitro Selection of RNA Aptamers That Bind to an Oligomeric State of Amyloid β-Peptide
• Construction and Control of Self-Assembly of Amyloid and Fibrous Peptides
• Construction of Two-Stranded α-Helix Peptides with L-α-Nucleobase Amino Acids
• SPECTROSCOPIC STUDY OF 3_ HELIX DEPSIPEPTIDES
• RESULTS OF LEFT VENTRICULAR FUNCTION AND CORONARY ARTERY STENOSIS IN PATIENTS WITH HIBERNATING MYOCARDIUM
• Osteopontin-derived Peptide SVVYGLR Induces Angiogenesis In Vivo
• Systematic Studies on Modification of Met-Residues during TFA Cleavage
• Construction of Novel High Throughput Recognition Systems Using Labeled Peptide Arrays Focusing on Protein Detection Chips
• A Novel Protein-Detecting Chip Platform Using Anomalous Reflection of Gold
• Construction of a PNA-DNA Hybrid Array Potential for a Novel Addressable Chip
• Studies on Fluorescent Dyes and Surface Chemistry focusing on Practical Peptide Array Preparation
• Peptide Microarrays Using Designed Libraries for Protein Detection
• Designed Peptide Microarrays and Protein Characterization Using Fingerprint Patterns
• Construction of a Protein-Detection System using Designed Peptides with Fluorescent Labels
• Recognition of Porphyrin or Protein using Peptides Derived from Antibody CDR
• Development of a Novel Simultaneous Multiple Separation and Synthesis Device with 96-Channel Column-like Reactors for High-throughput Library Construction
• Hexafluoroisopropyl Alcohol is a Useful Cosolvent with Dimethylformamide for Tryptic Synthesis of Peptides
• Synthesis of [D-Pyrenylalanine^]gramicidin S by Soild-Phase-Synthesis and Cyclization-Cleavage Method with Oxime Resin
• Difference in Self-Assembling Morphology of Peptide Nanorings
• Theoretical Prediction and Atomic Force Microscope Observations of the Protein Nanotube Consisting of Homo-_L-Amino Acid Penta-Peptide Nanorings
• Highly Efficient Characterization of Synthetic Peptides by the Time of Flight Matrix Assisted Laser Desorption Ionization Mass Spectrometry (MALDI-TOF), Practice, Advantages and Limitations
• A Menbrane Protein Model : Polypeptides with Four α-Helix Bundle Sturcture on 5,10,15,20-Tetrakis[2-(carboxymethoxy)phenyl]porphyrin
• De Novo Design and Synthesis of Four α-Helix Bundle Proteins with Flavin Function
• 5,10,15,20-Tetrakis(2-amino-6-methoxycarbonylphenyl)porphyrin. Synthesis and Separation of Atropisomers Useful for Porphyrin Architecture
• Dansyl and Indolyl Groups as a Probing Pair for Intersegmental Arrangement in Four- α-Helix Bundle Structure of a Polypeptide
• Efficient Preparation of αβαβ-Atropisomer of meso-Tetra(ο-aminophenyl)porphyrin
• Design of a Hybrid of Two α-Helix Peptides and Ruthenium Trisbipyridine Complex for Photo-induced Electron Transfer System in Bilayer Membrane
• Probing Behavior of 1-Pyrenylalanine for Interaction of Two α-Helices Anchored on a Bipyridyl Group
• A Hybrid of Amphiphilic α-Helical Peptides and meso-Tetra(α,α,α,α-o-carboxyphenyl)-porphyrin. Membrane-Penetrating Porphyrin-4α-Helix Artificial Protein
• Interaction of Basic Peptides Derived from Influenza Virus M1 Protein with DNA/RNA
• Interaction of Amphiphilic α-Helical Peptides with Phospholipid Membrane and Their DNA Binding Ability
• Cell-free Production of the Silkworm Sex Pheromone Bombykol
• Intracellular Transduction in the Regulation of Pheromone Biosynthesis of the Silkworm, Bombyx mori : Suggested Involvement of Calmodulin and Phosphoprotein Phosphatase
• Construction of the Artificial Peptides and RNAs Targeting Amyloid Peptides
• Structure and Function of Pro/Arg-rich Repeated Region in Antibiotic Bactenecin 5
• Enhanced Membrane-Perturbing Activities of Bundled Amphiphilic α-Helix Polypeptides on Interaction with Phospholipid Bilayer
• Peptide Synthesis Mediated by Thiolsubtilisin Using Peptide Thioester as Building Block
• Synthesis of Protected Peptides Containing Phosphoserine with Oxime Resin
• Complementary Assembly of Heterogenous Peptides into Amyloid Fibrils and Their Catalytic Function
• Design of Coiled-Coil Peptides Containing Nucleobase Interaction and Their Catalytic Function on Self-Replication
• Design of Peptides with L-α-Nucleobase Amino Acids and Their Selective Recognition of RNA
• Association and Guest-induced Dissociation of a Novel α-Helix Peptide Bearing Pyrene and γ-Cyclodextrin in the Side Chains
• Design and Synthesis of Peptides Containing Nucleobase Amino Acids and their Interaction with RNA
• Peptides Undergoing Secondary Structural Transition and Self-Assembly into Amyloid Fibril Based on Structural Complementarity
• An α-to-β Structural Transition and Amyloidogenesis of Peptides : Effects of Amino Acid Substitution on Self-replicating Organization
• Design and Synthesis of Peptide Misfolding from α to β Structure and Regulation by β-Cyclodextrin as Mini-Molecular Chaperone
• Design and Synthesis of 3α-helix Bundle Peptides Possessing a Hydrophobic Cavity
• De Novo Design, Synthesis and Characterization of Heme-Conjugated Two-α-Helix Peptides
• Annealing of Two-α-Helix Structure by Metal Ion Binding Regulated with Trifluoroethanol
• Design and Synthesis of Haem Binding Molecular Forceps Composed of Two-α-Helix Peptide
• Development of Peptide Arrays as Sensor Elements and Novel Chip-Materials Focusing on Practical Bio-Chip Production
• Effect of Difference in Nitrogen Media on Salt-Stress Response and Contents of Nitrogen Compounds in Rice Seedlings(Plant Nutrition)
• Physiochemical factors affecting the salt tolerance of Echinochloa crus-galli Beauv. var. formosensis Ohwi
• Design and Peroxidase-like Activity of 3α-Helix Hemoproteins
• Artificial Membrane Protein Functionalized with Electron Transfer System
• Gas-phase Microsequencing of Peptides and Proteins with a Fluorescent Edman-type Reagent, Fluorescein Isothiocyanate
• Chiral Assembly of Porphyrins Regulated by Amphiphilic α-Helix Peptides
• Construction of Porphyrin- and Flavin-Conjugated α-Helix Peptides
• Interaction of Lipophilized Mastoparan with Phospholipid Membranes
• Structure-designed Peptide Microarrays for Protein-Detection
• Enantioselective Conjugate Addition of Diethylzinc to Chalcones Using NiCl_2-Chiral β-Diamine Complex as Catalyst
• De Novo Design of α-Helical Peptides with Nucleobase Amino Acids that Specifically Recognize a Hairpin RNA
• 電極上に自己集積したフラビン修飾α-ヘリックスペプチドの電極反応特性
• Analysis of Polyamines, 1-Aminocyclopropane-1-carboxylic Acid and their Conjugated Forms in Floral Organs of Hibiscus syriacus L.
• N-D-Biotinyl-7-amino-4-methylcoumarin as a Novel Fluorigenic Substrate for the Determination of Biotinidase Activity
• Design and syntheses of fluorescent labeled peptides related to human prion and their interaction to infected mice brain homogenate
• Identification of Possible Sex Pheromone of the Yellow Stem Borer Moth, Scirpophaga incertulas (WALKER)(Lepidoptera : Pyralidae)
• Production of peptide and glycopeptide libraries and development of novel materials for microarrays focusing on protein detection
• Sex Pheromone of the Rice Stem Borer, Chilo suppressalis (WALKER) (Lepidoptera : Pyralidae) : the Third Component, Z-9-Hexadecenal
• Sex Pheromone Content in Female Chilo suppressails WALKER (Lepidoptera : Pyralidae) Reared on Artificial Diets
• Release Rate and Distance Effects of Evaporators with Z-11-Hexadecenal and Z-5-Hexadecene on Disruption of Male Orientation in the Rice Stem Borer Moth, Chilo suppressalis WALKER (Lepidoptera : Pyralidae)
• Disruption of Sex Pheromone Communication in the Rice Stem Borer Moth, Chilo suppressalis WALKER (Lepidoptera : Pyralidae), with Sex Pheromone Components and Their Analogues
• Disruption of Sex Attraction in the Rice Stem Borer Moth, Chilo suppressalis WALKER, with Components of the Sex Pheromone and Related Chemicals
• Construction and Characterization of a Peptide Library Related to the Human Prion Protein
• A Novel Protein Detection Platform Utilizing Anomalous Reflection of Gold
• P-292 FURTHER SYNTHETIC STUDIES ON (+)-PHOMOPSIDIN
• Application of Combinatorial Peptide Libraries to Prevention of Infectious Endocarditis, as an Example for Infection Control
• Fingerprint-Detection of Sugar-Binding Proteins Generated by Labeled Structured Glycopeptides Arrays
• Efficient Solid-Phase Synthesis and Purification of β-Amyloid Peptides by Improved Protocols with a Novel HPLC Column
• Construction of Green Fluorescent Protein (GFP) Variants with Amyloid β-Peptide Sequence
• Optimization for the Selective Removal of Sulfhydryl Protection in Fmoc-Solid Phase Peptide Synthesis for Side Chain Modification and/or Immobilization
• 3_10-Helix Nucleation in a Depsipeptide : Crystal Structure of Boc-(Leu-Leu-Ala)_2-(Leu-Leu-Lac)_3-OEt
• Nanomolar Aggregation and Neurotoxicity of Amyloid β Peptides with Site-Specific Modification of Oxidized Cholesterol
• Super-Secondary Structure with Amphiphilic β-Standards Probed by Pyrenylalanine
• Designed Peptide Libraries for Protein and Cell analyses
• A Non-proteinogenic Amino Acid, Mimosine and Mimosyl Peptides for Cosmeceutical Ingredients
• A Novel Peptide Array Using a Phage Display System for Protein Detection
• Design and Syntheses of Peptides as Bio-sensor Elements which can Detect the Structural Change of Prion Proteins
• Synthesis and Mass-Spectrometric Characterization of the Peptide-Vehicle, Peptide that Carry Molecules into Cells
• Studies of Bioconjugates Focusing on Drug Delivery ; Peptide-Vehicles Consisting of Recognition and Cell Penetrating Peptide-Modules with Anticancer Drugs
• Noncompetitive On-Chip Immunoassays for Detection of Nonlabeled Antibodies Based on the Excluded Volume Effect of the Target Itself
• Cell-adhesive hydrogels composed of peptide nanofibers responsive to biological ions
• Difference in Self-Assembling Morphology of Peptide Nanorings
• IR Study on Stacking Manner of Peptide Nanorings in Peptide Nanotubes
• Theoretical Prediction and Atomic Force Microscope Observations of the Protein Nanotube Consisting of Homo-l-Amino Acid Penta-Peptide Nanorings
• PREFACE
• Development of a Protein Structural Conversion Assay and Discovery of Bovine Brain Derived Peptides Accelerating Structural Conversions of the Recombinant Bovine Prion Proteins
• A peptide release system using a photo-cleavable linker in a cell array format for cell-toxicity analysis

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