マルチ・グラジエントエコーによる脳機能画像 : BOLD効果・流入効果の評価の試み

概要

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The pupose of this study was to evaluate blood oxygenation level-dependent(BOLD)contrast and the inflow effect in functional MRI. Nine normal volunteers underwent an activation test using right finger tapping on a 1.5T machine. A triple gradient echo sequence(TE=21, 44, 67msec)was repeated to obtain rest and activated images, and the functional image was calculated b subtraction. The excitation angle of the sequence was varied at 10 degree, 40 degree, and 70 degree. The activated region coincided with a cortical vein on 2D-TOF-MRA(v-group)or not (c-group). BOLD contrast was dominant in the both groups. The v-group had a larger inflow effect than the c-group. The activation ratio was independent of the excitation angle, which also suggested that BOLD contrast is dominant in functional MRI.
公益社団法人日本放射線技術学会の論文
1997-02-20