Gefitinib as a First Line of Therapy in Non-Small Cell Lung Cancer with Brain Metastases
スポンサーリンク
概要
- 論文の詳細を見る
Two Japanese women were diagnosed as having well-differentiated adenocarcinoma of the lung with brain metastases. Since it was considered they could not tolerate conventional chemotherapy, we administered gefitinib without any previous systemic therapy. In both patients gefitinib acted dramatically on all the lesions including the brain metastases, resulting in a marked decrease of the elevated CEA levels, and improvement of their quality of life. Retrospective evaluation of epidermal growth factor receptor expression levels by immunohistochemistry revealed positive results in both cases. Though gefitinib has been recommended for patients previously treated with chemotherapy, it should be considered feasible as a first line therapy.
- 社団法人 日本内科学会の論文
- 2004-08-01
著者
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KOHNO Nobuoki
Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima Uni
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Kohno Nobuoki
Department Of Molecular And Internal Medicine Graduate School Of Biomedical Sciences Hiroshima Unive
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Kohno Nobuoki
Department Of Internal Medicine Hiroshima University Graduate School Of Medicine
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ISHIDA Atsuko
Department of Pulmonary Medicine, Hiroshima City Hospital
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KANOH Koji
Department of Pulmonary Medicine, Hiroshima City Hospital
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NISHISAKA Takashi
Department of Pathology, Hiroshima Prefectural Hospital
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MIYAZU Yuka
Department of Pulmonary Medicine, Hiroshima City Hospital
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IWAMOTO Yasuo
Department of Pulmonary Medicine, Hiroshima City Hospital
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MIYAZAWA Teruomi
Department of Pulmonary Medicine, Hiroshima City Hospital
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Kanoh Koji
Department Of Pulmonary Medicine Hiroshima City Hospital
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Kanoh Koji
Department Of Chemistry And Chemical Engineering Faculty Of Technology Kanazawa University
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Miyazu Yuka
Department Of Pulmonary Medicine Hiroshima City Hospital
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Ishida Atsuko
Department Of Pulmonary Medicine Hiroshima City Hospital
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Iwamoto Yasuo
Department Of Electrical And Electronic Engineering Faculty Of Engineering Yamaguchi University
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Iwamoto Yasuo
Department Of Pulmonary Medicine Hiroshima City Hospital
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Miyazawa Teruomi
Department Of Pulmonary Medicine Hiroshima City Hospital
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Nishisaka Takashi
Department Of Pathology And Clinical Medicine Hiroshima Prefectural Hospital
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Kohno Nobuoki
Department Of Molecular And Internal Medicine Graduate School Of Biomedical Sciences Hiroshima Unive
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