Anti-Ku Antibody-Positive Scleroderma-Dermatomyositis Overlap Syndrome Developing Greves' Disease and Immune Thrombocytopenic Purpura

元データ 2002-12-01 社団法人 日本内科学会

概要

Graves disease (GD) has been reported to be frequently complicated with other autoimmune diseases. However, it is rarely complicated with scleroderma-polymyositis overlap syndrome. Recently, we encountered a 35-year-old woman who developed GD and immune thrombocytopenic purpura during follow-up observation of scleroderma-dermatomyositis overlap syndrome. Platelet counts recovered after high-dose γ-globulin therapy and bolus methylprednisolone therapy. The present case is the first report of a combination of scleroderma, dermatomyositis, GD, and immune thrombocytopenic purpura. The patient was anti-Ku antibody-positive and had relatively low natural killer T cell counts, both of which might contribute to the complication of multiple autoimmune diseases.(Internal Medicine 41: 1199-1203, 2002)

著者

NAKANISHI Shuhei Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima Uni
Watanabe Hiroshi Department of Cardiology, Niigata City General Hospital
Nakanishi Shuhei Department Of Molecular And Internal Medicine Graduate School Of Biomedical Sciences Hiroshima Unive
Nakanishi Shuhei 広島大学 医歯学総合研究科分子内科学
Kamei Nozomu Department Of Molecular And Internal Medicine Division Of Clinical Medical Science Programs For Appl
Fujikawa Rumi 広島大学 医歯学総合研究科分子内科学
Fujikawa Rumi 広島大学 第2内科
Fujikawa Rumi Department Of Molecular And Internal Medicine Graduate School Biomedical Sciences Hiroshima Universi
Kohno Nobuoki Department Of Molecular And Internal Medicine Graduate School Of Biomedical Sciences Hiroshima Unive
Kohno Nobuoki Department Of Molecular And Internal Medicine Hiroshima University Graduate School Of Biomedical Sci
Hiyama Keiko Department Of Molecular And Internal Medicine Division Of Clinical Medical Science Programs For Appl
Hiyama Keiko Department Of Cardiovascular Medicine Akanekai Tsuchiya Hospital
Kohno Nobuoki Second Department Of Internal Medicine Hiroshima University School Of Medicine
YAMANE Kminori Department of Molecular and Internal Medicine, Division of Clinical Medical Science Programs for App
YAMASHITA Yasuyo Department of Molecular and Internal Medicine, Division of Clinical Medical Science Programs for App
ISHIOKA Shinichi Ishioka Clinic
MENDOZA Ciro National Institute of Pulmonary and Enviromental Disease, Asuncion
KOHNO Nonuoki Department of Molecular and Internal Medicine, Division of Clinical Medical Science Programs for App
Mendoza Ciro National Institute Of Pulmonary And Enviromental Disease Asuncion
Yamane Kiminori Department Of Molecular And Internal Medicine Graduate School Of Biomedical Sciences Hiroshima Unive
Yamane Kiminori Department Of Molecular And Internal Medicine Graduate School Biomedical Sciences Hiroshima Universi
Yamane Kiminori Department Of Molecular And Internal Medicine Division Of Clinical Medical Science Programs For Appl
Kohno Nobuoki Department Of Molecular And Internal Medicine Division Of Clinical Medical Science Programs For Appl
Yamashita Yasuyo Department Of Molecular And Internal Medicine Division Of Clinical Medical Science Programs For Appl
Watanabe Hiroshi Department Of Molecular And Internal Medicine Graduate School Biomedical Sciences Hiroshima Universi
Watanabe Hiroshi Department Of Applied Chemistry And Bioengineering Graduate School Of Engineering Osaka City Univers

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