スギ樹皮の抗菌活性とその関連成分

概要

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Antifungal activity of the bark of Cyptomeria japonica D.Don was examined using four plantpathogenic fungi, namely Alternaria alternata, Pyricularia oryzae, Rhizoctonia solani and FusariumOxyporum cucumerinum. The growth of each fungus was inhibited by addition of the bark meal into the potato dextrose agar medium. Most of the antifungal activity disappeared from the bark after successive extractions with n-hexane, dichloromethane, ethanol and 70% aqueous acetone. All these extracts showed a certain extent of activity and the strongest activity was found in the hexane extract. By silica gel column chromatography and high performance liquid chromatography, an antifungal compound was isolated from the hexane extract and was identified as ferruginol.Quantitative analysis showed that a large amount of ferruginol was present in the commercially produced barks, ranging from 0.4 to 1.0% of dry weight. Therefore, ferruginol was assumed to playan important role in the antifungal activity of the bark.
日本木材学会の論文
2001-11-25