Regulation of the localization of Dbf2 and Mob1 during cell division of Saccharomyces cerevisiae
スポンサーリンク
概要
- 論文の詳細を見る
The mitotic exit network (MEN) governs Cdk inactivation. In budding yeast, MEN consists of the protein phosphatase Cdc14, the ras-like GTPase Tem1, protein kinases Cdc15, Cdc5, Dbf2 and Dbf2-binding protein Mob1. Tem1, Dbf2, Cdc5 and Cdc15 have been reported to be localized at the spindle pole body (SPB). Here we report changes of the localization of Dbf2 and Mob1 during cell division. Dbf2 and Mob1 localize to the SPBs in anaphase and then moves to the bud neck, just prior to actin ring assembly, consistent with their role in cytokinesis. The neck localization, but not SPB localization, of Dbf2 was inhibited by the Bub2 spindle checkpoint. Cdc14 is the downstream target of Dbf2 in Cdk inactivation, but we found that the neck localization of Dbf2 and Mob1 was dependent on the Cdc14 activity, suggesting that Dbf2 and Mob1 function in cytokinesis at the end of the mitotic signaling cascade.
- 日本遺伝学会の論文
著者
-
Toh-e Akio
Department Of Biological Sciences Graduate School Of Science The University Of Tokyo
-
Yoshida Satoshi
Department Of Bimolecular Science Faculty Of Engineering Gifu University
-
Yoshida Satoshi
Department Of Biological Sciences Graduate School Of Science The University Of Tokyo
-
Toh-e Akio
Department of Biological Science, Graduate School of Science, University of Tokyo
関連論文
- Identification of 1,3,6-Trinitropyrene as a Major Mutagen in Organic Extracts of Surface Soil from Nagoya City, Japan
- -0965-ASSESSMENT OF MYOCARDIAL VIABILITY BY THE EPICARDIAL AND BODY SURFACE MAPPING IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFTING : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- -0449-EVALUATION OF SEVERITY OF PATIENTS WITH MYOCARDIAL INFARCTION USING ANAEROBIC THRESHOLD
- Reactivities of Stable Rotamers. XLIII. Diazotization of 2-Methyl-2-(1,2,3,4-tetrachloro- and 1,4-dimethoxy-9-triptycyl)propylamine Rotamers^
- Blue Photoluminescence from Si-Doped Amorphous Silica Films by RF Sputtering
- Secretion of Aspergillus oryzae Alkaline Protease in an Osmophilic Yeast, Zygosaccharomyces rouxii(Biological Chemistry)
- Crystal and Molecular Structures of Novel Metal-Carbene Complexes III. Rh-Carbene Complexes and Cu Complex
- Crystal and Molecular Structures of Novel Metal-Carbene Complexes I. {1,1'-(Perhydropyrimidine-1,3-diyl-χC^2)bis[(alkyl/arylimino)methanethiolato-χ^2SS']} (triphenylphosphine)-Pt/Pd Complexes
- Absolute Conformation and Chiroptical Properties. VII. 9(1')-Msc and Psc Forms of 9-(2-Fluoro-1,1-dimethylethyl)-and 9-(1,1-Dimethylpropyl)-11,12-bis(methoxycarbonyl)-9,10-dihydro-9,10-ethenoanthracenes
- Comparative Analysis of Yeast PIAS-Type SUMO Ligases In Vivo and In Vitro
- Yeast Ulp1, an Smt3-Specific Protease, Associates with Nucleoporins^1
- Ybr267w is a New Cytoplasmic Protein Belonging to the Mitotic Signaling Network of Saccharomyces cerevisiae
- Forchlorfenuron, a phenylurea cytokinin, disturbs septin organization in Saccharomyces cerevisiae
- Nis1 encoded by YNL078W : a new neck protein of Saccharomyces cerevisiae
- GENETIC STUDY OF POLARIZED SECRETION OF THE YEAST Saccharomyces cerevisiae
- Autoimmune Pancreatitis Developing Remarkable Collateral Circulation Around the Pancreas
- Phospholipids and Their Derivatives as Mitogen and Motogen of Budding Tunicates
- Dynamics of the Hydration of Amino Alcohols and Diamines in Aqueous Solution
- LAS24/KOG1, a component of the TOR complex 1 (TORC1), is needed for resistance to local anesthetic tetracaine and normal distribution of actin cytoskeleton in yeast
- Induction of Osteogenic Protein-1 Expression by Interleukin-1β in Cultured Rabbit Articular Chondrocytes
- New Methods for Determination of Aerobic Microbial Concentration
- Jet ejection from droplets near the Leidenfrost temperature
- Defects in glycosylphosphatidylinositol (GPI) anchor synthesis activate Hog1 kinase and confer copper-resistance in Saccharomyces cerevisisae
- An improved integration replacement/disruption method for mutagenesis of yeast essential genes.
- High Expression Vectors for a Zygosaccharomyces rouxii Host(Microbiology & Fermentation Industry)
- Molecular Cloning of Lipase Genes from Alcaligenes denitrificans and Their Expression in Escherichia coli
- Genetic characterization of genes encoding enzymes catalyzing addition of phospho-ethanolamine to the glycosylphosphatidylinositol anchor in Saccharomyces cerevisiae
- Area-Selective Deposition of Diamond-Like Carbon Films onto Silicone Rubber by Femtosecond Laser
- Ribosomal DNA Plasmid Isolated from Zygosaccharomyces bailii and Its Use for Constructing Yeast Vectors Effective for Intergeneric Gene Transfer(Microbiology & Fermentation Industry)
- Intracellularly inducible, ubiquitin hydrolase-insensitive tandem ubiquitins inhibit the 26S proteasome activity and cell division
- Isolation and characterization of the yeast las21 mutants, which are sensitive to a local anestheticum, tetracaine
- Multi-Neutron and Proton Transfer Reactions in Deep Inelastic Heavy-Ion Collisions
- Regulation of the localization of Dbf2 and Mob1 during cell division of Saccharomyces cerevisiae
- Glyceraldehyde-3-phosphate Dehydrogenase Genes of Zygosaccharomyces rouxii: The Source of a Promoter for a Host-vector System for Z. rouxii
- Synergistic extraction of copper(II) and zinc(II) with tributyl phosphate and crown ether.