Genomic organization, transcription start sites, and chromosomal location of the Drosophila cortactin gene.
スポンサーリンク
概要
- 論文の詳細を見る
An actin filament binding protein cortactin was initially identified as a major phosphotyrosine-containing protein in v-Src-transformed chicken embryo fibroblast cells. The mouse, human, and Drosophila homologs were independently identified as a signaling molecule involved in a mitogenic response, as a product of a putative oncogene EMS1, and as a molecule interacting with a scaffolding protein ZO-1, respectively. In this report, we describe the cloning of the Drosophila cortactin gene, which consists of four exons and three introns, covering 3 kilobases in length. All exon-intron junctions are well matched with the GT/AG consensus sequence. S1 nuclease mapping revealed one major and several minor transcription start sites. The cytological location of the Crosophila cortactin gene is between chromosome segments 93B3 and 93B7.
- 日本遺伝学会の論文
著者
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Yamashita A
Hiroshima Univ. Hiroshima Jpn
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Yamashita Atsushi
Department Of Mechanical Engineering Shizuoka University
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Yamashita Atsushi
Department Of Fixed Prosthodontics Okayama University Dental School
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Ueda Ryu
Invertebrate Genetics Laboratory National Institute Of Genetics
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KATSUBE Takanori
Institute of Genetic Information, Kyushu Univeristy
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Hashimoto N
Mitsubishi Kagaku Inst. Life Sci. Tokyo Jpn
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Yamashita Atsushi
Neurogenetics Research Project, Mitsubishi Kasei Institute of Life Sciences
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Hashimoto Naoko
Neurogenetics Research Project, Mitsubishi Kasei Institute of Life Sciences
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Takahisa Manabu
Neurogenetics Research Project, Mitsubishi Kasei Institute of Life Sciences
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Ueda Ryu
Neurogenetics Research Project, Mitsubishi Kasei Institute of Life Sciences
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KATSUBE Takanori
National Institute of Radiological Sciences
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SASAKI Yuka
Neurogenetics Research Project, Mitsubishi Kasei Institute of Life Sciences
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TOGASHI Shin
Laboratory of Molecular Embryology, Department of Bioscience, Kitasato University
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Yamashita A
Department Of Mechanical Engineering Shizuoka University
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Yamashita A
Tohoku Univ. Sendai Jpn
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Togashi Shin
Laboratory Of Cell Biology Mitsubishi Kasei Institute Of Life Sciences
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Yamashita Atsushi
Department Of Metallurgy Graduate School Of Engineering Tohoku University
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Takahisa M
Neurogenetics Research Project Mitsubishi Kasei Institute Of Life Sciences
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Katsube T
National Institute Of Radiological Sciences
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Sasaki Yuka
Neurogenetics Research Project Mitsubishi Kasei Institute Of Life Sciences
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