FK463, a Novel Water-soluble Echinocandin Lipopetide: Synthesis and Antifungal Activity

スポンサーリンク

概要

• 論文の詳細を見る
• 1999-07-25

著者

• Takasugi H

  Fujisawa Pharmaceutical Co. Ltd. Osaka Jpn

• TAKASUGI Hisashi

  Medicinal Chemistry Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.

• Takasugi Hisashi

  Medicinal Chemistry Research Laboratories Fujisawa Pharmaceutical Co. Ltd.

• Tanaka H

  External Science Affairs Fujisawa Pharmaceutical Co. Ltd.

• MAKI Katsuyuki

  Medicinal Biology Research Laboratories

• OHKI Hidenori

  Medicinal Chemistry Research Laboratories

• TAWARA Shuichi

  Medicinal Biology Research Laboratories

• Ohki Hidenori

  Chemistry Research Laboratories Astellas Pharma Inc.

• Tawara S

  Pharmacology Research Laboratories Astellas Pharma Inc.

• TANAKA Hirokazu

  External Science Affairs, Fujisawa Pharmaceutical Co., Ltd.

• TOMISHIMA Masaki

  Medicinal Chemistry Research Laboratories

• YAMADA Akira

  Medicinal Chemistry Research Laboratories

• Maki Katsuyuki

  Pharmacology Research Laboratories Astellas Pharma Inc.

• Tomishima Masaki

  Chemistry Research Laboratories Astellas Pharma Inc.

• Yamada Akira

  Chemistry Research Laboratories Astellas Pharma Inc.

関連論文

• 10.酢酸菌のグルコン酸酸化にかかわる第3の膜酵素・FADグルコン酸脱水素酵素(第419回研究協議会研究発表要旨,ビタミンB研究委員会)
• Total Synthesis of Malformin C, an Inhibitor of Bleomycin-Induced G2 Arrest
• Fungal Malformins Inhibit Bleomycin-Induced G2 Checkpoint in Jurkat Cells(Highlighted paper selected by Editor-in-chief,Biochemistry)
• 1S-Ep05 耐熱性酢酸菌を使った酸化発酵による有用物質生産系の開発(伝統的醗酵微生物の新しい利用展開,シンポジウム,伝統の技と先端科学技術の融合)
• Biochemical and Spectroscopic Properties of Cyanide-Insensitive Quinol Oxidase from Gluconobacter oxydans
• Guadinomines, Type III Secretion System Inhibitors, Produced by Streptomyces sp. K01-0509 : II. Physico-chemical Properties and Structure Elucidation
• Guadinomines, Type III Secretion System Inhibitors, Produced by Streptomyces sp. K01-0509 : I. Taxonomy, Fermentation, Isolation and Biological Properties
• 2P030 酢酸菌Gluconobacter frateurii由来L-sorbose reductaseのX線結晶構造解析(蛋白質-構造機能相関,第48回日本生物物理学会年会)
• Lariatins, Novel Anti-mycobacterial Peptides with a Lasso Structure, Produced by Rhodococcus jostii K01-B0171
• Direct Comparison of the Pharmacodynamics of Four Antifungal Drugs in a Mouse Model of Disseminated Candidiasis Using Microbiological Assays of Serum Drug Concentrations
• Determination of Antifungal Activities in Serum Samples from Mice Treated with Different Antifungal Drugs Allows Detection of an Active Metabolite of Itraconazole
• In Vivo Antibacterial Activity of FK041, a New Orally Active Cephalosporin
• In Vitro Antibacterial Activity of FK041, a New Orally Active Cephalosporin
• Citrinamides, New Potentiators of Antifungal Miconazole Activity, Produced by Penicillium sp. FKI-1938
• Tensyuic Acids, New Antibiotics Produced by Aspergillus niger FKI-2342
• Fungal Citridone D Having a Novel Phenylfuropyridine Skeleton
• Tensidols, New Potentiators of Antifungal Miconazole Activity, Produced by Aspergillus niger FKI-2342
• P-527 CHEMICAL STUDY OF CITRIDONES, POTENTIATORS OF ANTI-FUNGAL MICONAZOLE ACTIVITY
• Anti-atherosclerotic Activity of Triacsin C, an Acyl-CoA Synthetase Inhibitor
• Verticipyrone, a New NADH-fumarate Reductase Inhibitor, Produced by Verticillium sp. FKI-1083
• Paecilaminol, a New NADH-Fumarate Reductase Inhibitor, Produced by Paecilomyces sp. FKI-0550
• The Selectivity of Beauveriolide Derivatives in Inhibition toward the Two Isozymes of Acyl-CoA: cholesterol Acyltransferase
• Selectivity of Pyripyropene Derivatives in Inhibition toward Acyl-CoA : cholesterol Acyltransferase 2 Isozyme
• Studies on Cerebral Protective Agents. X. Synthesis and Evaluation of Anticonvulsant Activities for Novel 4,5,6,7-Tetrahydrothieno[3,2-c]pyridines and Related Compounds
• Studies on Cerebral Protective Agents. IX. Synthesis of Novel 1,2,3,4-Tetrahydroisoquinolines as N-Methyl-D-aspartate Antagonists
• Cyslabdan, a New Potentiator of Imipenem Activity against Methicillin-resistant Staphylococcus aureus, Produced by Streptomyces sp. K04-0144 : II. Biological Activities
• Cyslabdan, a New Potentiator of Imipenem Activity against Methicillin-resistant Staphylococcus aureus, Produced by Streptomyces sp. K04-0144 : I. Taxonomy, Fermentation, Isolation and Structural Elucidation
• Novel Amidine Conjugates of the Ornithine Moiety of the Macrocyclic Antifungal Lipopeptidolactone FR901469
• Yaequinolones, New Insecticidal Antibiotics Produced by Penicillium sp. FKI-2140 : I. Taxonomy, Fermentation, Isolation and Biological Activity
• Synthesis and Biological Properties of a Novel Cephalosporin FR86521 Having Potent Activity Against Methicillin-resistant Staphylococcus aureus (MRSA)
• Inhibition of Lipid Droplet Accumulation in Mouse Macrophages by Stemphone Derivatives
• Structure-activity Relationships of Stemphones, Potentiators of Imipenem Activity against Methicillin-resistant Staphylococcus aureus
• P-539 ISOBISVERTINOL, A NOVEL INHIBITOR OF LIPID DROPLET ACCUMULATION IN MOUSE MACROPHAGES PRODUCED BY Aspergillus sp. FKI-1746
• Yaequinolones, New Insecticidal Antibiotics Produced by Penicillium sp. FKI-2140 : II. Structural Elucidation
• FR192752, a Novel Orally Active Cephalosporin Synthesis and Biological Properties
• FK463, a Novel Water-soluble Echinocandin Lipopetide: Synthesis and Antifungal Activity
• FK041, a Novel Orally Active Cephalosporin: Synthesis and Biological Properties
• Studies on 3'-Quaternary Ammonium Cephalosporins II Synthesis and Antibacterial Activity of 7β-[(Z)-2-(2-Aminothiazol-4-yl)-2-methoxyiminoacetamido]-cephalosporin Derivatives Bearing Various Ouaternary Ammonium Methyl Groups at the 3 Position
• Formaldehyde Elimination with Formaldehyde and Formate Oxidase in Membrane of Acetic Acid Bacteria(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
• Direct Observation of a Central Bare Zone in a Native Thick Filament Isolated from the Anterior Byssus Retractor Muscle of Mytilus edulis Using Fluorescent ATP Analogue
• Enzymatic Preparation of Metabolic Intermediates, 3-Dehydroquinate and 3-Dehydroshikimate, in the Shikimate Pathway
• Purification and Properties of NADP-Dependent Shikimate Dehydrogenase from Gluconobacter oxydans IFO 3244 and Its Application to Enzymatic Shikimate Production
• High Shikimate Production from Quinate with Two Enzymatic Systems of Acetic Acid Bacteria
• Conversion of Capsular Polysaccharide, Involved in Pellicle Formation, to Extracellular Polysaccharide by galE Deletion in Acetobacter tropicalis
• Growth Promoting Substance in Yeast Extract for Methylotrophic Growth of Candida boidinii
• P-540 SECONDARY METABOLITE PRODUCED BY A RARE FUNGUS, CALDARIOMYCES SP. FKA-35, ISOLATED FROM SUBTROPICAL SOIL
• A Tightly Bound Quinone Functions in the Ubiquinone Reaction Sites of Quinoprotein Alcohol Dehydrogenase of an Acetic Acid Bacterium, Gluconobacter suboxydans
• A Novel 3-Dehydroquinate Dehydratase Catalyzing Extracellular Formation of 3-Dehydroshikimate by Oxidative Fermentation of Gluconobacter oxydans IFO 3244
• Energy Metabolism of a Unique Acetic Acid Bacterium, Asaia bogorensis, That Lacks Ethanol Oxidation Activity
• Distinct Physiological Roles of Two Membrane-Bound Dehydrogenases Responsible for D-Sorbitol Oxidation in Gluconobacter frateurii
• Preparation of Enzymes Required for Enzymatic Quantification of 5-Keto-D-gluconate and 2-Keto-D-gluconate
• Use of a serum-based antifungal susceptibility assay to predict the in vivo efficacy of novel echinocandin compounds
• P-525 Efficient production of the anti-HIV protein actinohivin in recombinant Streptomyces strain
• 耐熱性酢酸菌を使った酸化発酵による有用物質生産系の開発(伝統的発酵微生物の新しい利用展開)
• Selective, High Conversion of D-Glucose to 5-Keto-D-gluoconate by Gluconobacter suboxydans
• Global Analysis of the Genes Involved in the Thermotolerance Mechanism of Thermotolerant Acetobacter tropicalis SKU1100
• Chitinase inhibitors : extraction of the active framework from natural argifin and use of in situ click chemistry
• Solid-phase total synthesis of the chitinase inhibitor Argadin using a supported acetal resin
• New verticilides, inhibitors of acyl-CoA : cholesterol acyltransferase, produced by Verticillium sp. FKI-2679
• New isochaetochromin, an inhibitor of triacylglycerol synthesis in mammalian cells, produced by Penicillium sp. FKI-4942 : II. structure elucidation
• New isochaetochromin, an inhibitor of triacylglycerol synthesis in mammalian cells, produced by Penicillium sp. FKI-4942 : I. Taxonomy, fermentation, isolation and biological properties
• The high mannose-type glycan binding lectin actinohivin : dimerization greatly improves anti-HIV activity
• Production of monapinones by fermentation of the dinapinone-producing fungus Penicillium pinophilum FKI-3864 in a seawater-containing medium
• Dinapinones, novel inhibitors of triacylglycerol synthesis in mammalian cells, produced by Penicillium pinophilum FKI-3864
• Spoxazomicins A-C, novle antitrypanosomal alkaloids produced by an endophytic actinomycete, Streptosporangium oxazolinicum K07-0460^T
• Solid-phase synthesis and biological activity of malformin C and its derivatives
• Xanthoradones, new potentiators of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Penicillium radicum FKI-3765-2 : II. Structure elucidation
• Xanthoradones, new potentiators of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Penicillium radicum FKI-3765-2 : I. Taxonomy, fermentation, isolation and biological properties
• Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-1 : II. Structure elucidation

もっと見る 閉じる

スポンサーリンク