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Drug Safety Research Laboratories, Eisai Co., Ltd. | 論文
- Stable Expression of Glutathione S-transferase P-form mRNA and TGF-α Immunohistochemical Expression are Useful Markers for Identification of Persistent Nodules from an Early Stage in Rat Hepatocarcinogenesis
- Clastogenicity of Quinoline Derivatives in the Liver Micronucleus Assay Using Rats and Mice
- Current Status of Carcinogenicity Assessment of Peroxisome Proliferator-Activated Receptor Agonists by the US FDA and a Mode-of-Action Approach to the Carcinogenic Potential
- Proteomic analysis for neuronal vacuolation induced by MK-801 in rat retrosplenial cortex
- A Comparision of the Results of Rat and Mouse Carcinogenicity Studies Conducted on Pharmaceuticals
- ラット再生肝および実験的肝障害モデルにおける細胞増殖マーカーとしてのPCNAとBrdUの有用性について
- P-15 Investigational study for hepatotoxicity in rats by E2011 repeated administration. 2) Bioactivation of benzothiazoles with amine structures in the Ames mutagenicity assay.(Proceedings of the 27th Annual Meeting)
- P6-44 The effects of chronic dietary restriction on biological characteristics in Crj:CD(SD)IGS rats(DRUG METABOLISM/CARCINOGENICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Collaborative work on evaluation of ovarian toxicity : 11) Two- or four-week repeated-dose studies and fertility study of ethylene glycol monomethyl ether in female rats
- Mechanism for benzothiazole derivative-induced hepatotoxicity in rats(SYMPOSIUM 1 : MECHANISMS OF HEPATOTOXIC EFFECTS)
- TOXICOLOGICAL RESPONSE OF RATS TO A NOVEL MONOAMINE OXIDASE TYPE-A INHIBITOR, (5R)-3-[2-((1S)-3-CYANO-1-HYDROX-YPROPYL)BENZOTHIAZOL-6-YL]-5-METHOXYMETHYL-2-OXAZOLIDI-NONE (E2011), ORALLY ADMINISTERED FOR 13 WEEKS
- "B-5 Modification of Drug Conjugation Pathway by Repeated Administration of Conjugating Enzyme Inhibitors in Rats.
- MORPHOLOGIC AND MORPHOMETRIC ANALYSIS OF CELLULAR AND SUBCELLULAR STRUCTURES OF RAT GASTRIC MUCOSA AFTER ADMINISTRATION OF E3810, A NOVEL PROTON PUMP INHIBITOR
- Modification of Mutagenicity by Fluorine-Substitution on Diazachrysene
- Report 4 : CASE STUDY OF CARCINOGENICITY BY INITIATION-PROMOTION MODEL (CARCINOGENlClTY STUDIES)
- Proteomic analysis for neuronal vacuolation induced by MK-801 in rat retrosplenial cortex
- DETERMINATION OF THE TIME AT WHICH CONGENITAL HYDROCEPHALUS IS INDUCED WITH HIGHER INCIDENCE DURING THE EARLY GESTATIONAL PERIOD IN RATS
- Estimation of cancer risk from somatic mutation assays.
- Investigational study for hepatotoxicity in rats by E2011 repeated administration. : 1) Aspects from involvement of phase II conjugating enzymes.