Sasaki Yusuke | Tohoku College Of Pharmacy

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概要

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著作論文

Synthesis of Endomorphin-2Analogues Containing Piperidinecarboxylic Acid (Pip) and 2-Azetidinecarboxylic Acid (Aze)
Synthesis and Biological Activity of Endomorphin-2 Analogues Containing Pro Mimics
Development of μ-Receptor Selective Opioid Mimetics Derived from Endomorphin Sequences
Synthesis and Biological Activity of Opioid Peptides Replaced Phenylalanine at Position 3 or 4 by 2, 6-Dimethylphenylalanine
Biological Properties of Opioid Peptides Replacing Tyr at Position 1 by 2,6-Dimethyl-Tyr
Synthesis and Bioactivity of Novel Type Pyrazinone Ring-Containing μ-Opioid Ligands
Generation of a Selective Agonist for Mu-Opioid Receptors by the Dimerization of 2', 6'-Dimethyl-L-Tyrosine through Pyrazinone
The Structure-Activity Relationship of Dmt-NH-X
Stereoselective Synthesis of Unique L-Tyrosine Analogs : Development of Novel μ-Opioid Receptor Ligands
Synthesis of Opioid Mimetics Containing a Pyrazinone Ring and Their Activities
Synthesis of Endomorphin-2 Analogues, Studies on Their Activities for Opioid Receptors, and Three Dimensional Structure
Receptor Binding Properties and Antinociceptive Effects of Chimeric Peptides Consisting of a μ-Opioid Receptor Agonist and an ORL1 Receptor Antagonist(Medicinal Chemistry)
Structural Studies of [2',6'-Dimethyl-L-tyrosine^1]Endomorphin-2 Analogues Containing Proline Mimics
The Structure-Activity Relationship of [Dmt^1]Endomorphin-2 Derivatives
The Structure-Activity Relationship of the Opioidmimetics Containing 2(1H)-Pyrazinone Ring as a Linker and Observation of Deamination during Synthesis
Design of Opioidmimetics : Dimerization of 2', 6'-Dimethyl-L-Tyrosine
Nociceptin and Dynorphin A Analogues with Dmp Substituted for N-Terminal Aromatic Residues
2',6'-Dimethylphenylalanine (Dmp) Can Mimic the N-Terminal Tyr in Opioid Peptides(Medicinal Chemistry)
Biological Activity of Dermorphin and Deltorphin-II Analogs Replaced Phenylalanine at Position 3 by 2,6-Dimethylphenylalanine
Solid Phase Synthesis of ψCH_2NH Pseudo-Peptide Analogs Using 2, 4-Dimethoxybenzyl Group as the Pseudobond Protecting Group
Identification of a Novel Carbohydrate-Mimicking Octapeptide from Chemical Peptide Library and Characterization as Selectin Inhibitor
Protection of ψ(CH_2NH) Peptide Bond with 2,4-Dimethoxybenzyl Group in Solid-Phase Peptide Synthesis
Relationship between structure and P-glycoprotein inhibitory activity of dimeric opioid peptides containing the Dmt-Tic pharmacophore
Receptor Affinity and Selectivity of Dermorphin-Related Analogs Containing 2', 6'-Dimethylphenylalanine in Position 1 or 3
Synthesis of Bivalent Ac-RYYRIK-NH_2 Analogues and the Optimal Spacer Length for ORL1 Receptor Binding
Novel [_D-Arg^2]dermorphin(1-4) Analogs with μ-Opioid Receptor Antagonist Activity

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