Itoh K | Medicinal Chemistiy Research Laboratories I Pharmaceutical Research Division Takeda Chemical Industr

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Design, Production, and Characterization of Recombinant Neocarzinostatin Apoprotein in Escherichia coli
Optically Active Antifungal Azoles. III. Synthesis and Antifungal Activity of Sulfide and Sulfonamide Derivatives of (2R, 3R)-2-(2,4-Difluorophenyl)-3-mercapto-1-(1H, 1,2,4-triazol-1-yl)-2-butanol
Optically Active Antifungal Azoles. I. Synthesis and Antifungal Activity of (2R, 3R)-2-(2,4-Difluorophenyl)-3-mercapto-1-(1H-1,2,4-triazol-1-yl)-2-butanol and Its Stereoisomers
Optically Active Antifungal Azoles. XIII.Synthesis of Stereoisomers and Metabolites of 1-[(lR, 2R)-2-(2, 4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1, 2, 4-triazol-1-yl)propyl]-3-[4-(1H-1-tetrazolyl)phenyl]-2-imidazolidinone (TAK-456)
Optically Active Antifungal Azoles. XII. Synthesis and Antifungal Activity of the Water-Soluble Prodrugs of l-[(lR, 2R)-2-(2, 4-Difluorophenyl)-2-hydroxy-l-methyl-3-(1H-1, 2, 4-triazol-1-yl)propyl]3-[4-(lH-1-tetrazolyl)phenyl]-2-imidazolidinone
Optically Active Antifungal Azoles. XI. An Alternative Synthetic Route for 1-[(1R, 2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-[4-(1H-1-tetrazolyl)phenyl]-2-imidazolidinone (TAK-456) and Its Analog
Optically Active Antifungal Azoles. X. Synthesis and Antifungal Activity of N-[4-(Azolyl)phenyl]- and N-[4-(Azolylmethyl)phenyl]-N'-[(1R, 2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-azolones
Synthesis and Biological Activity of (S)-2-Amino-3-(2,5-dihydro-5-oxo-4-isoxazolyl)propanoic Acid (TAN-950 A) Derivatives
Optically Active Antifungal Azoles. IX. An Alternative Synthetic Route for 2-[(1R, 2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-[4-(2,2,3,3-tetrafluoropropoxy)phenyl]-3(2H, 4H)-1,2,4-triazolone and Its Analogs
Optically Active Antifungal Azoles. VIII. Synthesis and Antifungal Activity of 1-[(1R, 2R)-2-(2,4-Difluoro- and 2-Fluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-(4-substituted phenyl)-2(1H, 3H)-imidazolones and 2-Imidazolidinones
Optically Active Antifungal Azoles. VII. Synthesis and Antifungal Activity of Stereoisomers of 2-[(1R, 2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-[4-(2,2,3,3-tetrafluoropropoxy)phenyl]-3(2H, 4H)-1,2,4-triazolone (TAK-
Optically Active Antifungal Azoles. VI. Synthesis and Antifungal Activity of N-[(1R, 2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-N'-(4-substituted phenyl)-3(2H, 4H)-1,2,4-triazolones and 5(1H, 4H)-tetrazolones
Preparation of a Monoclonal Antibody Specific for 5-Methyl-2'-deoxycytidine and Its Application for the Detection of DNA Methylation Levels in Human Peripheral Blood Cells
Comparison of Serum and Urinary Levels of Modified Nucleoside, 1-Methyladenosine, in Cancer Patients Using a Monoclonal Antibody-Based Inhibition ELISA
A Simple Determination Method of the Absolute Configuration of 1-Arylethanthiols by an Intramolecular CH/π Shielding Effect in ^1H-NMR of Diastereomeric Thiol Esters
P3-30 Demethylation of DNA in mouse gonocytes and clevage-like cell division
Expression of DNA Methyltransferase (Dnmt1) in Testicular Germ Cells during Development of Mouse Embryo
Increased Expression of Queuosine Synthesizing Enzyme, tRNA-Guanine Transglycosylase, and Queuosine Levels in tRNA of Leukemic Cells
Optically Active Antifungal Azoles. V. Synthesis and Antifungal Activity of Stereoisomers of 3-Azolyl-2-(substituted phenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanols
Optically Active Antifungal Azoles. IV. Synthesis and Antifungal Activity of (2R, 3R)-3-Azolyl-2-(substituted phenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanols
Optically Active Antifungal Azoles. II. Synthesis and Antifungal Activity of Polysulfide Derivatives of (2R, 3R)-2-(2,4-Difluorophenyl)-3-mercapto-1-(1H-1,2,4-triazol-1-yl)-2-butanol

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