TAMAMURA Hirokazu | Graduate School of Pharmaceutical Sciences, Kyoto University

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概要

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著作論文

Synthesis of a CC Chemokine, vMIP-II, Encoded by Kaposi's Sarcoma-Associated Herpesvirus and Its Biological Activity
The Chemokine Receptor CXCR4 as a Therapeutic Target for Several Diseases Including AIDS, Cancer and Rheumatoid Arthritis
New Leads of Low Molecular Weight CXCR4 Antagonists Based on Enhancement of the T140-based Pharmacophores
A New Strategy for Molecular-size Reduction of Bioactive Peptide, Using Two Orthogonal Libraries of Cyclic peptides
CXCR4 Antagonists Identified as Anti-Cancer-Metastatic Agents
Synthesis of Novel Anti-HIV Peptides Based on a CXCR4 Antagonist, T140, and Their SAR Study
Development of Specific CXCR4 Inhibitors Based on an Anti-HIV Peptide, T140, and Their Structure-Activity Relationships Study
Increase of R5 HIV-1 infection and CCR5 expression in T cells treated with high concentrations of CXCR4 antagonists and SDF-1
HIV-cell Fusion Inhibitors Targeted to the HIV Second Receptor : T22 and Its Downsized Analogs with High Activity
Synthesis of CXCR4 Antagonists, T140 Derivatives with Improved Biostability, and Their SAR Study
Development of Fusion-inhibiting Anti-HIV-1 Peptides Based on the Structure of Molecular Complex Involved in HIV-1-cell Fusion
Efficient Synthesis of Cyclic RGD Pseudopeptide with (E)-Alkene Dipeptide Isostere and Its Biological Activity
Design and Synthesis of Highly Active Anti-HIV Peptide Based on Gp41-C34 Peptide
Synthesis of Alkene Type Dipeptide Isosteres and Their Use to Probe the Structural Requirements of Peptide Transporter (PEPT1)
Stereoselective Synthesis of Diketopiperazine Mimetics as Promising Scaffolds for Drug Discovery Utilizing Organocopper-Mediated anti-S_N2' Reaction
Synthesis of ψ[(E)-CH=CMe]- and ψ[(Z)-CH=CMe]-type Dipeptide Isosteres and their Application to a Cyclic RGD Peptide
Synthesis of ψ[(E)-CMe=CMe]- and ψ[(E)-CMe=CH]-type Alkene Dipeptide Isosteres from a Chiral Amino Acid
Development of Low Molecular Weight CXCR4 Antagonists by Exploratory Structural Tuning of Cyclic Tetrapeptide-scaffolds
4-(Dimethylamino)phenacyl Group : New Photoremovable Protecting Group for Amines and Carboxylic Acids
Acid-catalyzed Ring-opening Reactions of β-Aziridinyl-α, β-enoates and Their Application
Stereoselective Synthesis of CF_2 or CHF-Substituted Phosphoamino Acids and Their Incorporation into Peptides
Synthesis of β-Secretase Inhibitors Containing a Hydroxyethylamine Dipeptide Isostere and their Structure-activity Relationship Studies
Efficient Induction of Pptide - Specific Cytotoxic T Lymphocytes by LPS - Activated Spleen Cells
Synthetic Studies on 7TM-GPCR (I) : Lipid Bilayer Assisted Membrane Peptide Ligation
Synthesis of (E)-Alkene trans-Xaa-Pro Mimetics Using Organocopper Reagents
Stereoselective Synthesis of Peptidomimetics with Hydroxyethylamine Dipeptide Isosteres Utilizing Aza-Payne Rearrangement and O, N-Acyl Transfer Reactions

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