初期動脈硬化斑まわりの血流と血管壁ずり応力分布の数値流体力学的シミュレーション

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Three dimensional unsteady calculations of the flow and the wall shear stress in the model of early or precursory lesions of atherosclerosis were carried out to understand the possible mechanisms of the contribution of the blood flow to atherogenesis. Complex patterns of the wall shear stress were obtained in models with various degrees of severity of the lesions. Even in the model of very early and hardly noticeable atherosclerosis, remarkable spatial differences of the shear stress were found in the vicinity of the plaque. It was concluded that the three dimensional unsteady nature of the blood flow in the region near the wall in the atherosclerotic plaque is highly complex and the computational method is useful to elucidate the mechanism of the interaction between the blood flow and the arterial wall.
東海大学の論文
1992-03-30

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