Seventy genetic variations in human microsomal and soluble epoxide hydrolase genes (EPHX1 and EPHX2) in the Japanese population

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概要

• 論文の詳細を見る
• Springer-Verlag Tokyoの論文
• 2001-06-01

著者

• Nakamura Yusuke

  Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, University of T

• IIDA Aritoshi

  Laboratory for Genotyping, SNP Research Center, The Institute of Physical and Chemical Research (RIK

• SAITO Susumu

  Laboratory for Genotyping, SNP Research Center, The Institute of Physical and Chemical Research (RIK

• SEKINE Akihiro

  Laboratory for Genotyping, RIKEN SNP Research Center

• Iida Aritoshi

  東京大学医科学研究所ヒトゲノム解析センター

• Aritoshi Iida

  Laboratory For Pharmacogenetics Snp Research Center The Institute Of Physical And Chemical Research

• Iida A

  Department Of Molecular Biology Institute Of Gerontology Nippon Medical School

• Iida Aritoshi

  理化学研究所遺伝子多型研究センター

• Sekine Akihiro

  Laboratory For Genotyping Riken Snp Research Center

• Saitoh Satoshi

  Laboratory For Genotyping Snp Research Center The Institute Of Physical And Chemical Research (riken

• MIURA Yukie

  Laboratory for Genotyping, SNP Research Center, Institute of Physical and Chemical Research

• Saito Susumu

  Laboratory For Snp Analysis Snp Research Center The Institute Of Physical And Chemical Research (rik

• Miura Yukie

  Laboratory For Genotyping Snp Research Center Institute Of Physical And Chemical Research

• EGUCHI Chiemi

  Laboratory for Genotyping, SNP Research Center, Institute of Physical and Chemical Research

• MITSUNOBU Yukari

  Laboratory for Genotyping, SNP Research Center, Institute of Physical and Chemical Research

• Sekine Akihiro

  Laboratory For Genotyping The Snp Research Center The Institute Of Physical And Chemical Research (r

• Nakamura Yusuke

  Laboratory For Molecular Medicine Human Genome Center The Institute Of Medical Science University Of

• Iida Aritoshi

  Laboratory For Bone And Joint Diseases Center For Genomic Medicine Riken

• Eguchi Chiemi

  Laboratory For Genotyping Snp Research Center Institute Of Physical And Chemical Research

• Nakamura Yusuke

  Univ. Tokyo Tokyo Jpn

• Nakamura Yusuke

  Laboratory Of Molecular Medicine Human Genome Center Institute Of Medical Science University Of Toky

• Miura Y

  Inst. Physical And Chemical Res. Tokyo Jpn

• Nakamura Yusuke

  Laboratory For Genotyping Riken Snp Research Center C/o Riken Yokohama Institute

• Sekine Akihiro

  Laboratory For Genotyping Riken Snp Research Center C/o Riken Yokohama Institute

関連論文

• OE-071 A Genom-Wide Association Study of SNPs in the risk of Atherosclerosis Obliterans(Heart failure, clinical(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• New correction algorithms for multiple comparisons in case-control multilocus association studies based on haplotypes and diplotype configurations
• A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population
• Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population
• High-resolution SNP and haplotype maps of the human gamma-glutamyl carboxylase gene (GGCX) and association study between polymorphisms in GGCX and the warfarin maintenance dose requirement of the Japanese population
• A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction
• Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction
• Association of VKORC1 and CYP2C9 polymorphisms with warfarin dose requirements in Japanese patients
• Japanese single nucleotide polymorphism database for 267 possible drug-related genes
• A high-throughput SNP typing system for genome-wide association studies
• PJ-152 A functional SNP in the Proteasome Subunit Alpha Type 6 Gene confers Risk of Myocardial Infarction in Japanese Population(Acute myocardial infarction, basic-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-212 Identification of a Novel non-coding RNA, MIAT, that Confers Risk of Myocardial Infarction(Genetics/Genetically engineered models/Gene therapy-2(H/M), The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-340 Large-Scale Genetic Association Study of 30 Inflammation-Related Genes for Myocardial Infarction Using Tag SNPs from HapMap Data(Genetics/Genetically engineered models/Gene therapy-1 (M) OJ57,Oral Presentation (Japanese),The 70th Anniversary Annual
• Fine-scale SNP map of an 11-kb genomic region at 22q13.1 containing the galectin-1 gene
• Identification of 46 novel SNPs in the 130-kb region containing a myocardial infarction susceptibility gene on chromosomal band 6p21
• Genome-wide association study to identify genes related to myocardial infarction
• A high-throughput SNP typing system for genome-wide association studies in patients with myocardial infarction
• High-density single-nucleotide polymorphism (SNP) map in the 96-kb region containing the entire human DiGeorge syndrome critical region 2 (DGCR2) gene at 22q11.2
• Isolation and mapping of a novel human kidney- and liver-specific gene homologous to the bacterial acetyltransferases
• Expression and chromosomal localization of KIAA0369, a putative kinase structurally related to Doublecortin
• EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth
• Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4
• High-resolution SNP map of ASPN, a susceptibility gene for osteoarthritis
• Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis
• Over-expression of cysteine proteinase inhibitor cystatin 6 promotes pancreatic cancer growth
• INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese
• Variations in the FTO gene are associated with severe obesity in the Japanese
• 1P-044 DNAメチル化維持を仲介するSRAドメインのヘミメチル化DNA認識について熱力学的解析(蛋白質・構造機能相関(1),第46回日本生物物理学会年会)
• Prediction of Sensitivity to STI571 among Chronic Myeloid Leukemia Patients by Genome-wide cDNA Microarray Analysis
• Microarray Analysis of Gene-expression Profiles in Diffuse Large B-cell Lymphoma : Identification of Genes Related to Disease Progression
• Chromosomal imbalances in adult T-cell leukemia revealed by comparative genomic hybridization: gains at 14q32 and 2p16-22 in cell lines
• Isolation of a Novel Gene Showing Reduced Expression in Metastatic Colorectal Carcinoma Cell Lines and Carcinomas
• Distinct pattern of gene expression in pyothorax-associated lymphoma (PAL), a lymphoma developing in long-standing inflammation
• Molecular cloning, mapping, and characterization of a novel human gene, MTA1-L1, showing homology to a metastasis-associated gene, MTA1
• Correlation of Allelic Loss with Poor Postoperative Survival in Breast Cancer
• Frequent Allelic Loss at 6q26-27 in Breast Carcinomas of the Solid-tubular Histologic Type
• Detailed Deletion Mapping of Chromosome Arm 3p in Breast Cancers : A 2-cM Region on 3p 14.3-21.1 and a 5-cM Region on 3p 24.3-25.1 Commonly Deleted in Tumors
• Correlation of Allelic Losses and Clinicopathological Factors in Primary Breast Cancers
• Mapping of a Breast Cancer Tumor Suppressor Gene Locus to a 4-cM Interval on Chromosome 18q21
• Allelic Loss on Chromosome 9q Is Associated with Lymph Node Metastasis of Primary Breast Cancer
• Genomic organization, mapping, and polymorphisms of the gene encoding human cartilage intermediate layer protein (CILP)
• A genomewide linkage analysis of Kawasaki disease : evidence for linkage to chromosome 12
• Combinational effect of genes for the renin-angiotensin system in conferring susceptibility to diabetic nephropathy
• Critical roles of T-LAK cell-originated protein kinase in cytokinesis
• Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis
• Enhanced SMYD3 expression is essential for the growth of breast cancer cells
• Multiplex Mutation Screening of the BRCA1 Gene in 1000 Japanese Breast Cancers
• Infrequent Mutation of the H-Cadherin Gene on Chromosome 16q24 in Human Breast Cancers
• Non-transmissible Sendai virus encoding granulocyte macrophage colony-stimulating factor is a novel and potent vector system for producing autologous tumor vaccines
• Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease
• Twenty single-nucleotide polymorphisms in four genes encoding cardiac ion channels
• Genetic variations in five genes involved in the excitement of cardiomyocytes
• Multiple single-nucleotide polymorphisms (SNPs) in the Japanese population in six candidate genes for long QT syndrome
• High-density SNP map of human ITR, a gene associated with vascular remodeling
• Gene-based SNP discovery as part of the Japanese Millennium Genome Project : identification of 190 562 genetic variations in the human genome
• Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines
• Identification and allelic frequencies of novel single-nucleotide polymorphisms in the DUSP1 and BTG1 genes
• Impact of CYP2D6^*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy
• Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia
• Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease
• No Evidence of Mutation in the Human PTC Gene, Responsible for Nevoid Basal Cell Carcinoma Syndrome, in Human Primary Squamous Cell Carcinomas of the Esophagus and Lung
• Complete cDNA sequence and genomic organization of a human pancreas-specific gene homologous to Caenorhabditis elegans sel-1
• Molecular cloning, expression, and mapping of a novel human cDNA, GRP17, highly homologous to human gadd45 and murine MyD118
• Isolation and characterization of a human cDNA encoding a protein homologous to the 7.2-kDa protein (subunit X) of bovine ubiquinol-cytochrome C reductase
• Loci on murine chromosomes 7 and 13 that modify the phenotype of the NOA mouse, an animal model of atopic dermatitis
• Allelic Loss at 1p34-36 Predicts Poor Prognosis in Node-negative Breast Cancer
• Correlation of genetic etiology with response to β-adrenergic blockade among symptomatic patients with familial long-QT syndrome
• A Gln/Arg polymorphism at codon 349 of the hBUBR1 gene
• Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis
• Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10 : therapeutic efficacy largely depends on radiosensitivity
• Mapping of a New Target Region of Allelic Loss to a 6-cM Interval at 21q21 in Primary Breast Cancers
• Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10
• Association of the RIP2 Gene with Childhood Atopic Asthma
• Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma
• Genomic organization and mapping of the human activin receptor type IIB (hActR-IIB) gene
• Twenty single nucleotide polymorphisms (SNPs) and their allelic frequencies in four genes that are responsible for familial long QT syndrome in the Japanese population
• Two Distinct Commonly Deleted Regions on Chromosome 13q Suggest Involvement of BRCA2 and Retinoblastoma Genes in Sporadic Breast Carcinomas
• An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway
• Nonrandom Chromosomal Imbalances in Esophageal Squamous Cell Carcinoma Cell Lines : Possible Involvement of the ATF3 and CENPF Genes in the 1q32 Amplicon
• Isolation and Characterization of Human NBL4, a Gene Involved in the β-Catenin/Tcf Signaling Pathway
• Analysis of APCL, a Brain-specific Adenomatous Polyposis Coli Homologue, for Mutations and Expression in Brain Tumors
• High-resolution SNP map in the 55-kb region containing the selectin gene family on chromosome 1q24-q25
• Stanniocalcin 2 overexpression in castration-resistant prostate cancer and aggressive prostate cancer
• Oncogenic role of NALP7 in testicular seminomas
• Novel 5α-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer
• Identification of brain-specific splicing variants of the hDLG1 gene and altered splicing in neuroblastoma cell lines
• Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer
• Characterization of SEZ6L2 cell-surface protein as a novel prognostic marker for lung cancer
• Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus
• Catalog of 300 SNPs in 23 genes encoding G-protein coupled receptors
• Catalog of 178 variations in the Japanese population among eight human genes encoding G protein-coupled receptors (GPCRs)
• Catalog of 680 variations among eight cytochrome P450 (CYP) genes, nine esterase genes, and two other genes in the Japanese population
• Catalog of 668 SNPs detected among 31 genes encoding potential drug targets on the cell surface
• Catalog of 238 variations among six human genes encoding solute carriers (hSLCs) in the Japanese population
• Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes : UGT2A1, UGT2B15, and UGT8
• 906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDHs) in the Japanese population
• Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters : ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8
• Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR)
• Thirteen single-nucleotide polymorphisms (SNPs) in the alcohol dehydrogenase 4 (ADH4) gene locus
• Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population

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