症例報告虫垂原発複合型腺神経内分泌癌の一治験例

概要

論文の詳細を見る
A５２-year-old man visited our hospital because of epigastralgia. The colonoscopic examinationrevealed an about ４cm-protruded lesion like SMT on the appendix and findings of the biopsy specimenwere compatible with the disgnosis of signet ring cell carcinoma. The primary lesion was unknownby upper gastrointestinal endoscopy, CT and PET, and the tumor markers were normalrevel. At laparotomy, severe peritoneal metastasis was revealed in the abdominal cavity, especiallyappendix. Severe stenosis of ileocecum was found, so we conducted ileocecal resection. Thehistopathological diagnosis was primary signet ring cell caicinoma of appendix, SE, N２, M０, P３,pStage Ⅳ. Postoperatively mFOLFOX was started, but allergic reaction was seen after１cycle.We started Panitumumab/CPT-１１and the patient attended our emergency department with shiveringchill and fever on treatment day１０. The next day he became shock state and CT revealed freeair. Operation might not save his life and we started supportive care. He died on the day. Thecause of his death was peritonitis by cancer perforation.
2012-04-25