Effect of Functional Groups on Biodegradation and Pre-osteoblastic Cell Response on the Plasma-Polymerized Magnesium Surface
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概要
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Magnesium (Mg) is light, has biocompatibility, and has mechanical properties close to those of natural bone. However, pure Mg severely corrodes in a physiological environment, which may result in fracture prior to substantial tissue healing. In this study, the Mg surface was modified by depositing a thin polymeric film containing COOH, NH2, and OH groups through plasma polymerization of acrylic acid, allyl amine, and allyl alcohol in order to improve its anticorrosion and bioactive properties. The --COOH group had a significant effect on bonelike apatite formation compared with --NH2 and --OH. It was also concluded that a bonelike-apatite formed COOH/Mg surface was more effective for reducing biodegradation rate than the other surfaces. The results of in vitro cell test revealed significantly enhanced cell proliferation and differentiation on the COOH/Mg and NH2/Mg surfaces compared with other surfaces.
- 2013-01-25
著者
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Kim Byung-hoon
Department Of Ceramic Engineering Chonnam National University
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Lee Kang
Department of Bioengineering and Robotics, Tohoku University, 6-6-01 Aza Aoba, Aramaki, Aoba-ku, Sendai 980-8579, Japan
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Ko Yeong-Mu
Department of Dental Materials, School of Dentistry, MRC Center, Chosun University, Gwangju 501-759, Republic of Korea
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