Properties of Magnetic Nanoparticles for Magnetic Immunoassays Utilizing a Superconducting Quantum Interference Device
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概要
- 論文の詳細を見る
Properties of magnetic nanoparticles are studied for application to magnetic immunoassays utilizing a superconducting quantum interference device (SQUID). In this application, a magnetic marker is made of magnetic nanoparticles, and the binding reaction between an antigen and its antibody is detected by measuring the magnetic field from the marker. Magnetization of an assembly of the particles is simulated when the effects of the thermal noise and the distribution of the particle size are taken into account. Magnetic signals from the assembly of the particles are clarified for three detection methods, i.e., susceptibility, relaxation and remanence. From the comparison with experimental results, it was shown that the demagnetization effect also significantly influences the magnetic signal from the particles. When these effects are taken into account, the simulation results agree semi-quantitatively with the experimental ones.
- Published by the Japan Society of Applied Physics through the Institute of Pure and Applied Physicsの論文
- 2005-01-15
著者
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Enpuku Keiji
Research Institute Of Superconductor Science And Systems Kyushu University
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Inoue Katsuhiro
Research Institute of Superconductor Science and Systems, Kyushu University, Hakozaki 6-10-1, Higashi-ku, Fukuoka 812-8581, Japan
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Enpuku Keiji
Research Institute of Superconductor Science and Systems, Kyushu University, Hakozaki 6-10-1, Higashi-ku, Fukuoka 812-8581, Japan
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Soejima Kazuyuki
Research Institute of Superconductor Science and Systems, Kyushu University, Hakozaki 6-10-1, Higashi-ku, Fukuoka 812-8581, Japan
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