Diffusion MR Imaging of White Matter Pathways:Visualization and Quantitative Evaluation
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概要
- 論文の詳細を見る
Diffusion tensor imaging (DTI) is one of the most promising MRI techniques for characterizing microstructural changes of cerebral white matter in brain research and clinical applications. The number of DTI studies is increasing, and more than 7500 articles have been published over the last decade. DTI enables visualization and characterization of white matter tracts in vivo by providing a unique image contrast on white matter that is unavailable with routine MR techniques; this allows three-dimensional (3D) visualization of neuronal pathways and quantification of the diffusion properties of white matter. Since its introduction in 1994, DTI has been used to study the structure of white matter and changes to its integrity within normal brains and brains affected by aging, stroke, dementia, psychiatric disorder, tumor, and other conditions. In this paper, the technical aspects and clinical applications of DTI are reviewed with a focus on clinical use and in vivo studies. The strengths and weaknesses of the approach are discussed and current extensions of the technology (q-space imaging and diffusional kurtosis imaging) are summarized.
- 順天堂医学会の論文
著者
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Kyogoku Shinsuke
Department Of Radiology Faculty Of Medicine Juntendo University
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Hori Masaaki
Department Of Radiology University Of Yamanashi
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Suzuki Michimasa
Department Of Radiology Juntendo University School Of Medicine
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Aoki Shigeki
Department Of Hepato-biliary-pancreatic Surgery Tokyo Medical And Dental University
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Kamiya Kouhei
Department Of Radiology National Center Of Neurology And Psychiatry
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YOSHIDA Mariko
Department of Applied Chemistry, Kyushu Institute of Technology
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KAMAGATA Koji
Department of Radiology, Juntendo University Hospital
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YOSHIDA MARIKO
Department of Radiology, Juntendo University Faculty of Medicine
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NISHIKORI AKIRA
Department of Radiology, Juntendo University Faculty of Medicine
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KUMAGAI FUMITAKA
Department of Radiology, Juntendo University Faculty of Medicine
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