大唾液腺腫瘍の臨床統計的観察

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We reviewed 133 cases of major salivary gland tumors treated in our department during the past 10years and investigated the accuracy and diagnostic impact of preoperative radiological examination. Of the 133 cases,110 were originated from the parotid gland and 23 were from the submandibular gland. According to the WHO classifications (1991), the most common benign tumor both in the parotid and the submandibular glands was pleomorphic adenoma, followed by Warthin's tumor. Mucoepidermoid carcinoma was the most common malignant tumor in both glands, followed by adenocarcinoma and adenoid cystic carcinoma.<BR>A combination of preoperative examination including CT, MRI, ultrasound echography, radioisotope imaging, and fine needle aspiration biopsy proved to be useful in making decisions about therapeutic plan. Surgery alone was performed in all benign tumor cases who accepted the indication. Surgical treatment modalities for the malignant tumors included lobectomy, total parotidectomy, and neck dissection for cervical lymph node metastasis. Postoperative radiotherapy and adjuvant chemotherapy were performed in some cases. Regarding the survival rate in malignant cases, all patients of stage I (n=14), II (n=3), and III (n=2) are alive, but 4 out of 9 patients of stage IV died. We experienced 37 cases (27.8%) of facial palsy,2 cases of salivary fistula and 4 cases of Frey's syndrome.34 cases (91.8%) of facial palsy were transient.
耳鼻咽喉科臨床学会の論文

大唾液腺腫瘍の臨床統計的観察

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