鼻アレルギー患者における肺機能検査:flow-volume patternとその定量化について

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We classified the flow-volume curves obtained from pulmonary function tests in patients with allergic rhinitis, and the significance of these classificaions in evaluating lower airway pathologic conditions is discussed. Type A, representing almost normal values, was scarce, while types B through E were found in significantly greater incidence. In nasal allergy patients, the lower airway was considered potentially hypersensitive and the flowvolume curve was suggestive of peripheral lower airway obstruction. In patients with pollinosis, symptoms suggestive of potential lower airway obstruction could be found throughout the year, while there was an additional finding of decline in vital capacity during the pollen season. However, the conventional indices of flow rates (V75, V50, V25, and so on) did not demonstrate the differences in flow rates between healthy subjects and nasal allergy patients because of the minutes difference. However, pattern analysis or comparison of MEFV curves was sufficiently to detect minor changes. Further, we described the quantitative analysis and automatic drawing of flow-volume data in the MEFV curve, as well as the objective evaluation from classifying the automatic drawing.
耳鼻咽喉科臨床学会の論文