肝動脈化学塞栓療法後，ウエルシュ菌による肝ガス壊疽を合併し溶血性ショックにより死亡した1例

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We report a case that died of septicemia complicated with massive hemolysis subsequent to hepatic gas gangrene due to Clostridium perfringens infection after transcatheter arterial chemoembolization (TACE) for hepatocellular carcinomas (HCCs).<BR>A man in his 60s who had been treated for several HCCs with radiofreqency ablation and TACE previously underwent TACE for newly diagnosed HCCs. He had a past history of multiple myeloma and bladder cancer. His clinical status and blood test data were unremarkable after TACE. He was discharged 4 days after TACE uneventfully. He complained of fever and abdominal pain 7 days after TACE. The next day, he was admitted to our hospital. CT scans demonstrated a large abscess with prominent gas collection in the liver, and blood test data indicated severe septicemia with massive hemolysis. He died 3 hours after admission. Bacterial blood culture test detected Clostridium perfringens, and autopsy revealed gas gangrene in the liver.<BR>Although Clostridium perfringens infection is expected to occur rarely after TACE, it may cause a fatal gas gangrene in the liver and is one of the complications that interventionists should keep in mind.
一般社団法人日本インターベンショナルラジオロジー学会の論文