The Relationship between Salivary Calcium Concentration and Differences in Bone Mineral Density Level in Female Rats
スポンサーリンク
概要
- 論文の詳細を見る
It has not yet been examined whether salivary calcium levels reflect changes in bone mass. The purpose of this study was to investigate the relationship between salivary calcium concentration and differences in bone mineral density due to estrogen deficiency and/or different calcium intake levels in female rats. In Experiment 1, the animals (n=14) were divided into an ovariectomized group (OVX) (n=8, 0.6% calcium diet) and a sham-operated group (Sham) (n=6, 0.6% calcium diet). The bone mineral density (BMD) levels of the tibia and lumbar spine were significantly lower in the OVX group than in the Sham group (p<0.001 and p<0.01, respectively), whereas there was no significant difference in the salivary calcium concentration between the two groups. In Experiment 2, after an ovariectomy operation, the animals (n=42) were randomized into five groups that received 0.01%, 0.1%, 0.6%, 1.2%, and 2.4% calcium diets (n=10, 10, 6, 8, and 8, respectively). The BMD levels of the tibia and lumbar spine were significantly lower in the 0.01% or 0.1% calcium diet intake groups than in the 0.6%, 1.2%, 2.4% calcium diet intake groups (all p<0.001), whereas there were no differences in the salivary calcium concentration among the groups. In conclusion, the salivary calcium level did not change during periods of decreasing BMD and bone strength induced by estrogen deficiency and/or calcium intake restrictions in female rats.
- 財団法人 学会誌刊行センターの論文
著者
-
Park Jong-hoon
Department Of Exercise Nutrition Graduate School Of Comprehensive Human Sciences University Of Tsuku
-
EZAWA Ikuko
Department of Biochemistry, Faculty of Dentistry, Tokyo Medical and Dental University
-
IIMURA Yuki
Comprehensive Human Sciences, University of Tsukuba
-
PARK Jong-Hoon
Department of Physical Education, Konkuk University
-
OMI Naomi
Comprehensive Human Sciences, University of Tsukuba
-
HATTORI Satoshi
Comprehensive Human Sciences, University of Tsukuba
-
AGATA Umon
Comprehensive Human Sciences, University of Tsukuba
-
TOKUDA Shuji
Health Education, Faculty of Education, Kagoshima University
関連論文
- Bone loss in a rat model of non-insulin-dependent diabetes mellitus,the OLETF(Otsuka Long-Evans Tokushima fatty strain)rat
- Menatetrenone Ameliorates Reduction in Bone Mineral Density and Bone Strength in Sciatic Neurectomized Rats
- Combination use of vitamin K_2 further increases bone volume and ameliorates extremely low turnover bone induced by bisphosphonate therapy in tail-suspension rats
- Menatetrenone Prevents Osteoblast Dysfunction in Unilateral Sciatic Neurectomized Rats
- Maintenance of trabecular structure and bone volume by vitamin K_2 in mature rats with long-term tail suspension
- Maggot Debridement Therapy for Postsurgical Wound Infection in Scoliosis : A Case Series in Five Patients
- Reliability of Lumbar Lordosis Measurement in Patients With Spondylolisthesis : A Case-Control Study Comparing the Cobb, Centroid, and Posterior Tangent Methods
- The Effect of Swimming on Cartilage Formation
- Estrogen deficiency and low-calcium diet increased bone loss and urinary calcium excretion but did not alter arterial stiffness in young female rats
- Effects of Physical Characteristics and Dietary Habits on Bone Mineral Density in Adolescent Girls