Cytologic Diagnosis of Nonpalpable Breast Cancer Presenting Nipple Discharge
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概要
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Methods and results of cytologic diagnosis of nonpalpable breast cancers presenting nipple discharge were studied. During the period between January 1980 and December 1995, 61 consecutive cases of nonpalpable breast cancer with nipple discharge were reviewed at Sapporo Medical University Hospital.<BR>For smear cytology (S method), the rates of correct diagnosis (Class III b, IV and V) and definitive diagnosis (Class IV and V) were 11.5% and 8.2% respectively, whereas those for ductal washing cytology (W method) were 32.8% and 16.4%. The rates of detection of atypical cells (Class III a, III b, IV, V) for both methods were 54.2%, which were not satisfactory. A fiberoptic ductoscopy system was developed in August 1989, and the diagnostic rates for the S and W methods have decreased since the introduction of endoscopy for diagnosis. However, the rates of correct and definitive diagnosis were 45.5% (10/22) and 36.4% (8/22) respectively for curette cytology under endoscopic observation (C method), which allows successful detection of minimal intraductal cancers in peripheral ducts.<BR>The number of minimal breast cancers detected has recently increased due to the development of diagnostic imaging, and the curette method has become an important new diagnostic procedure for obtaining cell samples from intraductal lesions of the breast. The development of diagnostic imaging and cytologic diagnosis is prerequisite for early detection and diagnosis of nonpalpable breast cancers presenting nipple discharge.
- 日本乳癌検診学会の論文
日本乳癌検診学会 | 論文
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