Clinical Study of Neurological Complications Associated with Mumps

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概要

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• This report was based on 45 cases of neurolo-gical complications associated with mumps infec-tion, which were observed at the Departments of Pediatrics of Keio University, Yokosuka Kyosai Hospital and Yokohama Municipal Hospital from January 1960 to December 1973.<BR>These results were as follows.<BR>1) The seasonal incidence was more frequent in the spring and summer.<BR>2) The illness occurred most commonly be-tween the third and eighth years of ilfe.<BR>3) The onset of neurological complications was most common between two days before and se-ven days after the appearance of salivary glan-dular enlargement.<BR>4) Based on the clinical and laboratory findings, the complications were further diagnosed as asep-tic meningitis (33 cases, 73.3%), deafness (bilate-ral 2 cases, unilateral 1 case, 6.7%), encephalitis or encephalopathy (3 cases, 6.7%), febrile convul-sion (3 cases, 6.7%), meningsm (2 cases, 4.4%), and unilateral seizure (1 case, 2.2%).<BR>5) All of the 33 cases with aseptic meningitis showed a good recovery, whereas the cases with deafness and those with encephalitis or encepha-lopathy had poor prognosis, the loss of hearing was always persistent in the 3 cases of deafness, although 2 cases had only a short follow-up ob-servation (3 weeks, 4 months). Two of the 3 cases with encephalitis or encephalopathy were fatal.<BR>Deafness and encephlitis or encephalopathy associated with mumps were reviewed in the literature and the need for administration of live attenuated mumps vaccine to children was dis-cussed.

• 一般社団法人 日本小児神経学会の論文

一般社団法人 日本小児神経学会 | 論文

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