Secondary Encephalitides Other Than Measles Encephalitis

概要

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Asu survey was made on 63 patients of the secondary encephalitides admitted to our department during the ten years from the clinical and immunological view points.<BR>Etiologically, sixty-three patients consist from 13 of measles, 12 of mumps, 11 of varicella, 5 of rubeo1a infantum, 2 of herpes simplex, 1 of rubella, 5 of other exanthematous infection, and 14 of vacclnatlon.<BR>Although the incidence, age of onset, latent period, prognosis, and sex ratio were variable dependingon the each antecedent infection, most patients be1onged to the age between 4 and 5 years<BR>An interesting relationship was found between the latent period, sex incidence, and the clmical forms. The cases with latent period over 8 days were predominantly female and encephalitic form and those within 8 days were male and meningitic form.<BR>In some recent cases including 2 of subacute sclerosing encephalitis and one varicella encephalitis, immunoglobulin-G (Ig-G) concentration, Ig-G/albumin ratio, and the activity of macrophage inhibition factor (MIF) were determined in CSF.Cases with SSPE and varicella encephalitis had higher level of Ig-G, Ig-G/albumin ratio, and MIF in CSE These findings suggested that some immunological reaction took place in the central nervous system as a cause of these encephlitides.
一般社団法人日本小児神経学会の論文