Domperidone peroral therapy for gastroesophageal reflux in severely retarded children.:Domperidone Peroral Therapy for Gastroesophageal

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Seven severely retarded children, ranging in age from seven months to six years, with recurrent vomiting are reported. The diagnosis of gastroesophageal reflux was made on upper gastrointestinal series and the pH monitoring of the distal esophagus.<BR>We evaluated the effect of domperidone on recurrent vomiting in six patients. Vomiting disappeared in four cases. We sometimes found gastroesophageal reflux by the pH monitoring even after the disappearance of vomiting. Therefore we must decide carefully when domperidone therapy is discontinued.
一般社団法人日本小児神経学会の論文