Long-term prognosis of convulsive disorders in the first year of life: Febrile and afebrile seizures.

概要

論文の詳細を見る
A follow-up study was made on 166 cases with febrile and afebrile seizures in the first year of life. All patients were followed until 6 years of age or older. The subjects were divided into four small groups: group A, febrile convulsions only; group B, febrile convulsions, evolving to afebrile seizures; group C, afebrile seizures with normal mental and physical development, and seizures stopped before the age of three; group D, afebrile seizures other than group C. Comparison among these four groups were made with regard to etiologic factors, clinical features, EEG and long-term prognosis.<BR>Afebrile seizures subsequently developed in 48.5% of patients with febrile convulsions in the first year. From the analysis of factors associated with these four groups, group A was characterized by 1) cryptogenic etiology, 2) boy preponderance, 3) positive family history, 4) late onset after 6 months of age, and 5) very good prognosis. Group D was characterized by 1) symptomatic etiology, 2) a lower incidence of family history, 3) a higher incidence of early onset within the first 6 months, and 4) poor prognosis for mental and physical development and seizures. Group B had both features of A and D. Group C showed features different from group A and might have something in common group D with very good prognosis.
一般社団法人日本小児神経学会の論文