Semi-quantification of Endolymphatic Size on MR Imaging after Intravenous Injection of Single-dose Gadodiamide: Comparison between Two Types of Processing Strategies
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概要
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Purpose: Many inner ear disorders, including Ménière's disease, are believed to be based on endolymphatic hydrops. We evaluated a newly proposed method for semi-quantification of endolymphatic size in patients with suspected endolymphatic hydrops that uses 2 kinds of processed magnetic resonance (MR) images. Methods: Twenty-four consecutive patients underwent heavily T2-weighted (hT2W) MR cisternography (MRC), hT2W 3-dimensional (3D) fluid-attenuated inversion recovery (FLAIR) with inversion time of 2250 ms (positive perilymph image, PPI), and hT2W-3D-IR with inversion time of 2050 ms (positive endolymph image, PEI) 4 hours after intravenous administration of single-dose gadolinium-based contrast material (IV-SD-GBCM). Two images were generated using 2 new methods to process PPI, PEI, and MRC. Three radiologists contoured the cochlea and vestibule on MRC, copied regions of interest (ROIs) onto the 2 kinds of generated images, and semi-quantitatively measured the size of the endolymph for the cochlea and vestibule by setting a threshold pixel value. Results: Each observer noted a strong linear correlation between endolymphatic size of both the cochlea and vestibule of the 2 kinds of generated images. The Pearson correlation coefficients (r) were 0.783, 0.734, and 0.800 in the cochlea and 0.924, 0.930, and 0.933 in the vestibule (P<0.001, for all). In both the cochlea and vestibule, repeated-measures analysis of variance showed no statistically significant difference between observers. Conclusion: Use of the 2 kinds of generated images generated from MR images obtained 4 hours after IV-SD-GBCM might enable semi-quantification of endolymphatic size with little observer dependency.
- 日本磁気共鳴医学会の論文
著者
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Ikeda Mitsuru
Department Of Medical Information And Medical Records Nagoya University Hospital
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Naganawa Shinji
Department Of Radiology Nagoya University Graduate School Of Medicine
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Sone Michihiko
Department Of Otorhinolaryngology Nagoya University Graduate School Of Medicine
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Suzuki Kojiro
Department Of Advanced Energy Graduate School Of Frontier Sciences The University Of Tokyo
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Bokura Kiminori
Department Of Radiology Nagoya University Graduate School Of Medicine
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Nakashima Tsutomu
Department Of Cardiology Nagoya University Graduate School Of Medicine
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NAKAMICHI Rei
Department of Radiology, Nagoya University Graduate School of Medicine
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YOSHIDA Tadao
Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine
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HOMANN Georg
Department of Radiology, Nagoya University Graduate School of Medicine
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