Impact of the Standardized Uptake Value on the Body Trunk with Truncation Error of μ-map in the Positron Emission Tomography/Computed Tomography: Phantom Studies

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Purpose: The aim of this study was evaluate to impact of standardized uptake value (SUV) on the body trunk with truncation error of μ-map for CT attenuation correction (CTAC) in whole-body 2-deoxy-2-[18F] fluoro-D-glucose (18F-FDG)-positron emission tomography (PET)/CT with use of anthropomorphic phantom. Methods: We used body phantom (2.5 MBq/l) including simulated tumor targets (11.25 MBq/l) and arm phantom. The CT scan was used with a field of view (FOV) of 50 cm. The μ-maps were created by assuming a state of the arm protruding from the FOV (Pmap). A 3D-PET scan with an emission time of 20 min was performed. The PET images were then reconstructed with CTAC, and with and without scatter correction. We evaluated the relationship to Pmap size and the count of simulated tumors and background (B.G.) in PET images which reconstructed the use of each Pmap, respectively. Results: The count of simulated tumor (large) with scatter correction was decreased to 1.3% (Pmap: 15 mm) and 8.8% (Pmap: 35 mm). Then, the count severe reduction was 86.9% in Pmap of 65 mm. The same trend was shown by simulated tumor (middle, small) and B.G. The count of the simulated tumor (large) without scatter correction decreased to 1.3% (Pmap: 15 mm), 6.4% (Pmap: 35 mm) and 13.1% (Pmap: 65 mm). Conclusion: Truncation error by μ-map for CTAC in whole-body 18F-PET/CT caused a decrease of the SUV on the body trunk used for attenuation and scatter correction in the PET images.