Basal Insulin Requirements after Progesterone Treatment in a Type 1 Diabetic Pregnant Woman

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概要

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• We herein report the case of a 37-year-old type 1 diabetic pregnant woman treated with an insulin pump. Although the patient's glycemic control deteriorated following progesterone treatment for the prevention of preterm delivery and miscarriage, it was improved by adjusting the basal insulin rate on the days of progesterone treatment. Excess progesterone is known to impair both insulin sensitivity and secretion. The present case is the first report to evaluate deterioration of glycemic control induced by progesterone treatment and to determine the dose of insulin required in a type 1 diabetic pregnant woman whose insulin secretion was completely depleted.

• 社団法人 日本内科学会の論文

著者

• Shimomura Iichiro

  Department Of Internal Medicine And Molecular Science Graduate School Of Medicine Osaka University

• MATSUOKA TAKA-AKI

  Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine

• Kasami Ryuichi

  Department Of Metabolic Medicine Osaka University Graduate School Of Medicine

• Kaneto Hideaki

  Department Of Biochemistry Osaka University Medical School

• Fujita Yukari

  Department Of Chemistry Faculty Of Science Gakushuin University

• Yasuda Tetsuyuki

  Department Of Internal Medicine And Therapeutics Osaka University Graduate School Of Medicine

• Matsuhisa Munehide

  Diabetes Therapeutics And Research Center Tokushima University

• Sasaki Shugo

  Department of Internal Medicine, Kansai Rosai Hospital, Japan

• Tabuchi Yukiko

  Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Japan

• Fujisawa Keiko

  Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Japan

• Kuroda Akio

  Diabetes Therapeutics and Research Center, The University of Tokushima, Japan

• Matsuhisa Munehide

  Diabetes Therapeutics and Research Center, The University of Tokushima, Japan

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