Juvenile-onset Hereditary Pheochromocytoma-paraganglioma Syndrome
スポンサーリンク
概要
- 論文の詳細を見る
It is insufficient to distinguish benign tumors from malignant pheochromocytoma using histological analyses of resected tissue alone. We experienced an 18-year-old woman who complained of severe headaches in whom hypertension was revealed. She was suspected of having a malignant tumor based on her clinical characteristics, despite showing no evidence of metastatic lesions. The patient was diagnosed with an aggressive form of hereditary pheochromocytoma-paraganglioma syndrome (HPPS) based on immunohistochemical analyses and genetic testing. The present case indicates that conducting genetic testing, including SDHB mutation analyses, is required to determine the prognosis in patients highly suspected of having HPPS.
- 社団法人 日本内科学会の論文
著者
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Okada Yosuke
The First Department Of Internal Medicine School Of Medicine University Of Occupational And Environm
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ISOBE KAZUMASA
Molecular Laboratory Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukub
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NISHIDA KEIKO
The First Department of Internal Medicine, School of Medicine, University of Occupational & Environm
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Tanaka Yoshiya
The First Department Of Internal Medicine School Of Medicine University Of Occupational & Enviro
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Arao Tadashi
The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
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Takekoshi Kazuhiro
Molecular Clinical Pathology, Graduate School of Comprehensive Human Sciences (Institute of Clinical Medicine), University of Tsukuba, Japan
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Tanaka Yoshiya
The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
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Okada Yosuke
The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
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Sugisawa Chiho
The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
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Mori Hiroko
The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
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Isobe Kazumasa
Molecular Clinical Pathology, Graduate School of Comprehensive Human Sciences (Institute of Clinical Medicine), University of Tsukuba, Japan
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