Complete Resolution of Dermatomyositis with Refractory Cutaneous Vasculitis by Intravenous Cyclophosphamide Pulse Therapy
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概要
- 論文の詳細を見る
Cutaneous ulcers associated with vasculitis are rarely reported in adult-onset dermatomyositis (DM), and are often resistant to treatment, resulting in a poor prognosis. There is no general treatment strategy and the effects of various treatments have never been confirmed histopathologically. A 43-year old man with DM developed refractory multiple cutaneous ulcers which were revealed as vasculitis by skin biopsy. Repeated intravenous cyclophosphamide pulse therapy (IV-CY) without high-dose corticosteroid therapy resulted in complete resolution of the ulcers without adverse effects or severe complications. A repeat biopsy confirmed complete remission of vasculitis. Repeated IV-CY is a useful treatment for induction of clinical remission of DM with cutaneous vasculitis.
- 社団法人 日本内科学会の論文
著者
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Tanaka Yoshiya
The First Department Of Internal Medicine School Of Medicine University Of Occupational & Enviro
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Saito Kazuyoshi
The First Department Of Internal Medicine School Of Medicine University Of Occupational And Environm
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Tsujimura Shizuyo
The First Department Of Internal Medicine School Of Medicine University Of Occupational And Environm
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Tsujimura Shizuyo
The First Department of Internal Medicine, University of Occupational & Environmental Health, School of Medicine
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