Prediction of Dysphagia Severity: An Investigation of the Dysphagia Patterns in Patients with Lateral Medullary Infarction
スポンサーリンク
概要
- 論文の詳細を見る
Objective In order to identify the factors that influence the swallowing function in patients who develop Wallenberg syndrome (WS) following lateral medullary infarction (LMI), we examined various patient characteristics, including the passage pattern abnormality (PPA) of a bolus through the upper esophageal sphincter (UES). Methods Fifty-four pure LMI patients with dysphagia participated in this study. PPA, defined as the failure of bolus passage through the UES corresponding to the intact side of the medulla, was identified during videofluorographic swallowing evaluations of each patient. On brain magnetic resonance imaging, the subjects' lesions were classified vertically into three levels and horizontally into seven levels in relation to the involvement of the ambiguous and/or solitary nuclei. Logistic regression analyses were performed for age, sex, PPA and the vertical and horizontal sites of the lesions. Results In terms of severity, 15 subjects were categorized as having mild dysphagia, 26 subjects were categorized as having moderate dysphagia and 13 were categorized as having severe dysphagia. Subjects with cephalic lesions, greater vertical spread of the lesion and PPA were more likely to have severe dysphagia. PPA and a greater vertical spread of the lesion were related to the severity of the functional outcome (p<0.01). The horizontal extent of the lesion was not strongly related to the prognosis. Conclusion The presence of PPA in LMI patients is suggestive of abnormalities in the swallowing pattern and, in turn, damage to the medullary central pattern generator. The presence of PPA and a greater vertical spread of the lesion can be useful predictors of severe dysphagia.
著者
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Imai Keisuke
Department Of Emergency Medicine Acute Stroke Center Of Kyoto First Red Cross Hospital
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Kimura Miyuki
Department of Applied Chemistry, Faculty of Engineering, Nagasaki University:Department of Bacteriology, Nagasaki Institute of Tropic Medicine
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Fujimoto Yasushi
Department of Otolaryngology, Nagoya University, Japan
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Makino Masahiro
Department of Neurology, Japanese Red Cross Kyoto Daini Hospital, Japan
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Yokozeki Megumi
Department of Neurology, Kyoto Prefectural University of Medicine, Japan
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Oshima Fumiko
Department of Neurology, Kyoto First Red Cross Hospital
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Imai Keisuke
Department of Neurology, Japanese Red Cross Kyoto Daiichi Hospital, Japan
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Hamanaka Masashi
Department of Neurology, Japanese Red Cross Kyoto Daiichi Hospital, Japan
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Fujiu-Kurachi Masako
Department of Rehabilitation, Niigata University of Rehabilitation, Japan
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Oshima Fumiko
Department of Neurology, Japanese Red Cross Kyoto Daiichi Hospital, Japan
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