Analysis of Novel Soybean Sprout Allergens That Cause Food-Induced Anaphylaxis
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概要
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Several soybean- and soy product-based allergens have been reported. However, a full analysis of soybean sprout allergens remains to be conducted. Soybean sprout allergy is related to soy intolerance. Here we report a case of anaphylaxis induced by soybean sprouts in a 49-year-old woman. We performed a skin prick test, allergen-specific IgE identification using microarray assay (ImmunoCAP®-ISAC), SDS-PAGE, and immunoblotting for allergen analysis. The ImmunoCAP®-ISAC microarray assay detected Gly m 4 in the soybean sprout. However, immunoblotting revealed two 100-kDa protein bands that did not correspond to Gly m 4 (17 kDa). Therefore, we propose that this patient was not only sensitized to the Gly m 4 allergen, but also to the novel 100-kDa protein.
- 社団法人 日本食品科学工学会の論文
著者
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Kojima Takashi
Kanagawa Prefectural Institute of public Health
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KUMASAKA Kenichi
Kanagawa Prefectural Institute of Public Health
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Ikezawa Zenro
Department Of Dermatology Yokohama City University Hospital
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Aihara Michiko
Department Of Dermatology Juntendo University School Of Medicine
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ITAGAKI Yasuharu
Department of Environmental Immuno-Dermatology, Yokohama City University, Graduate School of Medicine
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NAKAGAWARA Ryoko
Department of Environmental Immuno-Dermatology, Yokohama City University, Graduate School of Medicine
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KOHNO Masumi
Yokohama City University Medical Center
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MATSUKURA Setsuko
Yokohama City University Medical Center
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MIYAZAWA Maki
Kanagawa Prefectural Institute of Public Health
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