Detection of Peripartum Myocardial Burden by Vector-Projected 187 Channel Electrocardiography and Serum NT-proBNP
スポンサーリンク
概要
- 論文の詳細を見る
There is no reliable method of screening for pregnant women at high risk of developing severe myocardial disorders. In this study, we used vector-projected 187 channel electrocardiography (DREAM-ECG) and serum biochemical markers to evaluate peripartum myocardial burden in pregnant women. Forty-one pregnant women were examined at 36-37 weeks gestation (GW36), 7 days postpartum (PPD7), and 1 month postpartum (PPM1). Ten non-pregnant control women were assessed at a single time point. Heart rate, sympathetic index, and repolarization index (RTc dispersion) were quantified using the DREAM-ECG system, and serum levels of NT-proBNP, cardiac troponin T, estrogen, and progesterone were determined. Heart rate and the sympathetic index decreased from GW36 to PPM1 (<I>P</I> = 0.0031). The repolarization index decreased over time and was greater than in non-pregnant controls (31 ± 13 ms). Estrogen and progesterone at PPD7 and PPM1 were significantly lower than those at GW36 (<I>P</I> < 0.0001, <I>P</I> < 0.001). NT-proBNP at PPD7 was greater than at GW36 (median 29 pg/mL at GW36, 86 pg/mL at PPD7), and decreased at PPM1 in comparison to PPD7 (median 18.5 pg/mL). Troponin T was in the normal range during the whole period (< 0.003 ng/mL). In conclusion, these results indicate that the peripartum myocardial burden in pregnant women does not return to normal nonpregnant levels by PPM1. We propose that both repolarization indexes such as RTc dispersion by DREAM-ECG and serum biochemical markers may identify pregnant women at high risk of developing severe myocardial damage in the peripartum period.
著者
-
Kikuchi Akihiko
Department Of Electrical And Electronics Engineering Sophia University
-
Itoh Manabu
Department Of Cardiovascular Surgery Shin-koga Hospital
-
Nakai Kenji
Department Of Clinical Pathology
-
Fukushima Akimune
Department Of Obstetrics And Gynecology Iwate Medical University
-
Sugiyama Toru
Department Of Chemical Engineering Kyoto University
-
Terata Miyuki
Department of Obstetrics and Gynecology, Iwate Medical University
-
Fukushima Akimune
Department of Clinical Genetics, Iwate Medical University
関連論文
- Development and Significance of a Fetal Electrocardiogram Recorded by Signal-Averaged High-Amplification Electrocardiography
- Comparison of biochemical markers and cervical length for predicting preterm delivery
- Pregnancy complicated by diffuse chorioamniotic hemosiderosis : Obstetric features and influence on respiratory diseases of the infant
- Sudden fetal hemorrhage from umbilical cord ulcer associated with congenital intestinal atresia
- Dichorionic twin fetuses with VACTERL association
- Massive pericardial effusion in an early gestational fetus having intrapericardial diaphragmatic hernia
- Giant hemangioma of the fetal neck, mimicking a teratoma
- Fractal tumor growth of ovarian cancer : sonographic evaluation(Session16 Oncology8)
- IS-76 Clinical Usefulness of Three-dimensional Ultrasound with Saline Solution Infusion Sonohysterography(3D-SHG)for Volume Estimation of Uterine Submucous Myomas
- Ti-mask Selective-Area Growth of GaN by RF-Plasma-Assisted Molecular-Beam Epitaxy for Fabricating Regularly Arranged InGaN/GaN Nanocolumns
- OE-380 Signal-Averaged Vector-Projected 187-channel High-Resolution Electrocardiogram Can Evaluate Recovery-Time and Tpeak-end Dispersion(ECG/Body surface potential mapping/Holter-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Free peritoneal cyst with histologic properties of amniotic epithelium observed in a woman pregnant with twins
- Newly Developed Signal-Averaged Vector-Projected 187-Channel Electrocardiogram Can Evaluate the Spatial Distribution of Repolarization Heterogeneity
- Development of a Signal-Averaged Vector-Projected 187-Channel High-Resolution Electrocardiogram for the Evaluation of the Spatial Location of High-Frequency Potentials and Abnormal Ventricular Repolarization
- PE-317 Spectral Map of Atrial Fibrillation and Atrial flutter by a 187-channel Signal-averaged Vector projected ECG compared with 64 Channel Magnetocardiogram(ECG/Body surface potential mapping/Holter(04)(A),Poster Session(English),The 72nd Annual Scienti
- PE-316 Development of 187-Channel Signal-Averaged Vector-Projected Electrocardiogram for the Evaluation of the Spatial Distribution of Repolarization Heterogenelty(ECG/Body surface potential mapping/Holter(04)(A),Poster Session(English),The 72nd Annual Sc
- PJ-235 Recovery Time Dispersion and Arrhythmic Event in Patients with Cardiac Resynchronization Therapy Device(PJ040,CRT/ICD 2 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PCR and PCR-RFLP techniques targeting the DNA topoisomerase II gene for rapid clinical diagnosis of the etiologic agent of dermatophytosis
- The Application of Magnetic Cell Sorter (MACS) to Detect Fetal Cells in Maternal Peripheral Blood
- IS-98 The Application of Magnetic Cell Sorter(MACS)to Detect Fetal Cells in Maternal Peripheral Blood. Is This Technique Useful for Non-invasive Prenatal Diagnosis during Early Gestation Periods?
- Tissue engineering for myocardial regeneration
- DOUBLE LAYERED CO-CULTURE OF HEPATOCYTES AND ENDOTHELIAL CELLS
- A Novel Tool of Temperature-Responsive Cell Culture Surfaces and Its Application to Matrix Biology
- Growth of Self-Organized GaN Nanostructures on Al_20_3(0001)by RF-Radical Source Molecular Beam Epitaxy
- Two-Dimensional Growth of GaN on Various Substrates by Gas Source Molecular Beam Epitaxy Using RF-Radical Nitrogen Source
- Substrate Nitridatiorn Effects on GaN Growm on GaAs Substrates by Molecular Beam Epitaxy Using RF-Radical Nitrogen Source
- Fetal hydrops associated with congenital pulmonary myofibroblastic tumor
- PE-152 Signal-Averaged Vector-Projected 187-channel High-Resolution Electrocardiogram Can Evaluate Space Distribution of High-Frequency Low-Amplitude Potential(ECG/Body surface potential mapping/Holter-4, The 71st Annual Scientific Meeting of the Japanese
- IS-92 An Approach to Automated Fetal Cell Detection in Maternal Blood
- Can Synthetic Aperture Magnetometry Images on Magnetocardiography Identify the Space Locations of Myocardial Viability?
- SPATIAL DISTRIBUTION OF LATE POTENTIALS ASSESSED BY SIGNAL-AVERAGED BODY SURFACE MAPPING
- Absorption Coefficient Measurements of MgZnCdSe II-VI Compounds on InP Substrates and Quantum Confined Stark Effect in ZnCdSe/MgZnCdSe Multiple Quantum Wells
- Absorption Coefficient Measurements of MgZnCdSe II-VI Compounds on InP Substrates and Quantum Confined Stark Effect in ZnCdSe/MgZnCdSe Multiple Quantum Wells
- OE-113 Ethnic Differences in the VKORC1 Gene Polymorphism and an Association With Warfarin Dosage Requirements in Patients With Cardiovascular Surgery(Thromboembolism/Antithrombotic therapy/Thrombolysis(01)(H),Oral Presentation(English),The 72nd Annual Sc
- PE-359 Three-dimensional High Frequency Magnetic Field of Terminal QRS-end by 64-channel Magnetocardiography May Demonstrate the Space Location of Arrhythmogenic Substrate(ECG/Body surface potential mapping/Holter-4 (A) PE60,Poster Session (English),The 7
- PE-252 Three-dimensional Frequency Characterization of Atrial Fibrillation by Magnetocaddiogram is Valuable for a Restoration to Sinus Rhythm after Pulmonary Vein Isolation(ECG/Body surface potential mapping/Holter-5 (A) PE42,Poster Session (English),The
- Three-dimensional Recovery Time Dispersion Map of Maximum dV/dt in The ST Segment by Magnetocardiography May Demonstrate a Injured Myocardium(ECG/Body Surface Potential Mapping/Holter 3 (A), The 69th Annual Scientific Meeting of the Japanese Circulation S
- PE-354 Clinical Significance Of CYP2C9 Gene Polymorphisms By Rapid Cycle Real-Time PCR In Patients Receiving Warfarin Therapy(Cardiovascular Pharmacology, Basic/Clinical 4 (H) : PE61)(Poster Session (English))
- PE-225 Current Density Map Using Space Filter Method on Magnetocardiography Can Detect Non-invasive Anatomical Localisation of Accessory Pathway and Source Origin(ECG/Body Surface Potential Mapping/Holter 4 (A) : PE39)(Poster Session (English))
- Improvement of Crystal Quality of RF-Plasma-Assisted Molecular Beam Epitaxy Grown Ga-Polarity GaN by High-Temperature Grown AIN Multiple Intermediate Layers
- High-Quality GaN on AlN Multiple Intermediate Layer with Migration Enhanced Epitaxy by RF-Molecular Beam Epitaxy
- Serum levels of cystatin C in patients with malignancy
- Significance of Cytochrome P450 2C9 (CYP2C9) Polymorphisms by Rapid Cycle Real-Time PCR in Patients with Hypertension under Losartan Medication
- MALDI-TOF Mass Spectrometry Can Accurately Detect Highly Multiplexed Genotyping of SNPs for Coronary Artery Disease by a Multiplex PCR
- Growth and Characterization of ZnCdSe/BeZnTeII-VI Compound Type-II Superlattices on InP Substrates and Their Application for Visible Light Emitting Devices : Semiconductors
- Characterization of Overgrown GaN Layers on Nano-Columns Grown by RF-Molecular Beam Epitaxy : Semiconductors
- Growth and Characterization of Nitrogen-Doped MgSe/ZnSeTe Superlattice Quasi-Quaternary Oil InP Substrates and Fabrication of Light Emitting Diodes
- Crystal Growth and Characterization of II-VI Compound Light Emitting Diodes with Novel Superlattice Quasi-Quaternary Cladding Layers on InP Substrates
- Substrate Misorientation Effect on Self-Organization of Quantum-Wires in (GaP)m/(InP)m Short Period Binary Superlattices
- Raman Scattering from Interface Phonons in GaInP / AlInP Superlattice
- 600-nm-Range GaInP/AlInP Strained Quantum Well Lasers Grown by Gas Source Molecular Beam Epitaxy
- 600 nm-Range GaInP/AlInP Multi-Quantum-Well (MQW) Lasers Grown on Misorientation Substrates by Gas Source Molecular Beam Epitaxy (GS-MBE)
- Orientation Dependence of In-Plane Tensile Properties of Paper : Experiments and Theories
- Effects of Strain Rate on the Compressive Stress-Strain Loops of Several Engineering Plastics
- Bio-functionalized surface designs necessary for applications in regenerative medicine
- Adenosine-Induced Changes of the Phase Transition of Poly(6-(acryloyloxymethyl)uracil) Aqueous Solution
- Risk Factors for Development of Pre-Diabetic State from Normal Glucose Regulation
- Glucose-Sensitive Lower Critical solution Temperature Changes of Copolymers Composed of N-Isopropylacrylamide and Phenylboronic Acid Moieties
- Characterization of Silane Coupling Agent Layers Formed on Silica Surface
- Mitral valve repair for broad, asymmetrical prolapse in the posterior mitral leaflet
- Aortic Dissection Late after Aortic Valve Replacement
- Excitonic Polariton Dispersion in ZnSe Determined by the Resonant Raman Scattering under Two-Photon Excitation of Excitonic Molecules
- New Application Method of Fibrin Glue for More Effective Hemostasis in Cardiovascular Surgery : Rub-and-Spray Method
- Off-Pump Coronary Artery Bypass Grafting in Octogenarians
- Massive cystic lymphangiomas of a fetus
- Two cases of a fetus with sirenomelia sequence
- Orientation Dependence of In-Plane Tensile Properties of Paperboard and Cardboard : Experiments and Theories
- High Strain-rate Compressive Response of Friction Stir Welded AA6061-T6 Joints : Effect of Welding Parameter
- Prenatal diagnosis of Holt-Oram syndrome : Role of 3-D ultrasonography
- Monochorionic twin fetuses showing a reversal of donor-recipient phenotypes in severe twin-twin transfusion syndrome without oligo-polyhydramnios sequence
- Fetus with prenatally diagnosed posterior mediastinal lymphangioma : Characteristic ultrasound and magnetic resonance imaging findings
- Perioperative Coronary Artery Spasm in Off-pump Coronary Artery Bypass Grafting and its Possible Relation with Perioperative Hypomagnesemia
- InGaN/GaN Multiple Quantum Disk Nanocolumn Light-Emitting Diodes Grown on (111) Si Substrate
- Effective separation of peptides using highly dense thermo-responsive polymer brush-grafted porous polystyrene beads
- Smectic A Formation by Twin Dimers Assuming U-shaped Conformation
- Clinical features of polyhydramnios associated with fetal anomalies
- Pulmonary Embolism Associated with Sjogren's Syndrome in Pregnancy
- Optically Pumped Green (530-560nm) Stimulated Emissions from InGaN/GaN Multiple-Quantum-Well Triangular-Lattice Nanocolumn Arrays
- Selective-Area Growth of GaN Nanocolumns on Si(111) Substrates Using Nitrided Al Nanopatterns by RF-Plasma-Assisted Molecular-Beam Epitaxy
- PE-386 Polymorphisms in the VKORC1 gene are associated with warfarin dosage requirements in patients receiving anticoagulation(Cardiovascular pharmacology, basic/clinical-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-235 Multiple Genetic Predisposition Including Metabolic, Cytokine, Growth Factor, and Cogulation-fibrinolysis Disorder are Relevant in Severe ICA Stenosis(Atherosclerosis, clinical-9 (H) PE40,Poster Session (English),The 70th Anniversary Annual Scienti
- Successful prenatal and perinatal management of a massive cervicofacial teratoma
- Effect of Welding Speed on Tensile Properties and Fracture Behavior of Friction Stir Welded AA6061-T6 Joints
- High Strain-Rate Compressive Stress-Strain Response of Bulk Epoxy Structural Adhesive
- High Strain-Rate Compressive Properties and Constitutive Modeling of Selected Polymers
- Body Surface Two-Dimensional Spectral Map of Atrial Fibrillation Using Vector-Projected 187 Channel Electrocardiography
- Risk Stratification of Ventricular Fibrillation by Two-Dimensional Functional Image of Repolarization Dispersion and T-Wave Alternance Using Synthesized 187-Channel ECG
- Confinement of Optical Phonons Observed by Raman Scattering in GaN/AlN Multiple Quantum Disk Nanocolumns
- Enlarging amniotic fluid 'sludge' in preterm labor associated with severe course of sepsis and recurrent tension pneumothorax in the infant
- Two-Dimensional Body Surface Dominant Frequency by Vector-Projected 187-Channel Electrocardiography May Evaluate a Characteristics of Atrial Fibrillation
- Erythematous and bullous rash strongly indicating toxic epidermal necrolysis associated with the use of intravenous ritodrine hydrochloride
- Prenatal findings in a fetus with contiguous gene syndrome caused by deletion of Xp22.3 that includes locus for X-linked recessive type of chondrodysplasia punctata (CDPX1)
- Case of chronic ectopic pregnancy diagnosed in which the complete shape of the fetus was visible by ultrasonography
- Understanding biological systems using ultrasound : complex dynamical systems view
- Detection of Peripartum Myocardial Burden by Vector-Projected 187 Channel Electrocardiography and Serum NT-proBNP
- Renal Dysfunction, Recovery Time Dispersion and Ventricular Arrhythmias in Heart Failure Patients Receiving Cardiac Resynchronization Therapy Defibrillator
- High Strain-Rate Compressive Behavior of Bulk Structural Adhesives: Epoxy and Methacrylate Adhesives
- The mechanism of the reaction of (aryloxy)trimethylstannane with benzyl bromide giving aryl benzyl ether.
- Serum levels of cardiac troponin I and other marker proteins in patients with chronic renal failure
- Constitutive Modeling of Mechanical Behavior of Friction Stir Welded AA2024-T3 Butt Joints under In-plane Tension and Through-thickness Compression