Posterior Disconnection in Early Infancy to Treat Intractable Epilepsy With Multilobar Cortical Dysplasia:—Three Case Reports—
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概要
- 論文の詳細を見る
Extensive multilobar cortical dysplasias occasionally occur in children and can induce seizure onset in early infancy, causing severe epileptic encephalopathy. Surgical interventions in early infancy, such as disconnection of large parts of the brain, are challenging because of the degree of invasiveness and carry greater risks in infants compared with older children. Here we report the successful treatment of intractable epilepsy with multilobar cortical dysplasias in the posterior cortex by posterior disconnection in three infants (age 3 months). The patients showed good postoperative recovery and exhibited excellent seizure control at follow-up evaluation within a year after surgery. Developmental catch-up was also achieved and no early complications have been detected to date. Use of the posterior disconnection technique for early-stage extensive multilobar cortical dysplasias can result in good seizure control and developmental progress with little perioperative morbidity. However, the efficacy of this surgical technique needs to be verified with long-term follow up after surgery.
著者
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Sugai Kenji
Department Of Child Neurology National Center Hospital For Mental Nervous And Muscular Disorders Nat
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Kaido Takanobu
Department Of Neurosurgery Nara Medical University
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Otsuki Taisuke
Department Of Neurosurgery National Center Hospital Of Neurology And Psychiatry
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Nakagawa Eiji
Department Of Child Neurology National Center Hospital For Mental Nervous And Muscular Disorders Nat
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Sasaki Masayuki
Department Of Anesthesiology Gunma University Graduate School Of Medicine
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Kaneko Yuu
Department Of Neurosurgery Ncnp
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Takahashi Akio
Departmen Of Neurosurgery Gunma University School Of Medicine
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LIANG Qin-Chuan
Department of Neurosurgery, Tangdu Hospital, The Fourth Military Medical University
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ENOKIZONO Takashi
Department of Child Neurology, National Center Hospital of Neurology and Psychiatry, National Center of Neurology and Psychiatry
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SASAKI Masayuki
Department of Child Neurology, National Center Hospital of Neurology and Psychiatry, National Center of Neurology and Psychiatry
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OTSUKI Taisuke
Department of Neurosurgery, National Center Hospital of Neurology and Psychiatry, National Center of Neurology and Psychiatry
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TAKAHASHI Akio
Department of Neurosurgery, National Center Hospital of Neurology and Psychiatry, National Center of Neurology and Psychiatry
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