THE NORMAL VALUES OF 15 KINDS OF PLASMA PROTEINS OF THE JAPANESE PEOPLE

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We estimated the normal values of 15k inds of plasma protein in 166 cases of healthy Japanese individuals using the single radial immunodiffusion method. The normal values of each plasma portein of the persons aged from 20 to 60 were as follows: prealbumin 22±5mg/dl, albumin 4091±581mg/dl, α1-acid-glycoprotein 60±22mg/dl, α1-antitrypsin 253±73mg/dl, haptoglobin 152±83mg/dl, ceruloplasmin 37±8mg/dl, α2-macroglobulin 231±65mg/dl, α2HS-glycoprotein 36±8mg/dl,β1A-globulin 94±26mg/dl, transferrin 237±44mg/dl, hemopexin 47±14mg/dl,β2-glycoprotein (Type 1) 10.4±2.1mg/dl, IgM 157±58mg/dl, IgA 273±69mg/dl, IgG 1264±182mg/dl, The observations made on the increase and decrease of protein based on age differences were as follows: albumin, transferrin, α1-antitrypsin tended to decrease, while IgG, α2-macroglobulin and IgA tended to increase correspondingly with aging. Another observation based on the differences of sex showed that only albumin recorded a higher value in the male, while in the female α2-macroglobulin, β1A-globulin,β2-glycoprotein, IgM and IgG showed higher values. A racial comparison of plasma proteins between Japanese and caucasians was made, showing that the values of many proteins were generally higher in western peoples, especially significant were hemopexin, transferrin and β2-glycoprotein, among 15 kinds of plasma proteins with the exception of immunoglobulins.
Japan Society of Clinical Chemistryの論文