A Nanoneedle can be Inserted into a Living Cell without Any Mechanical Stress Inducing Calcium Ion Influx
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概要
- 論文の詳細を見る
An influx of calcium ions into a living cell occurs when the cell is deformed mechanically by compressing, indenting or stretching. The calcium ions are taken up through mechanosensitive channels sensing deforming signals. The calcium ion is a key trigger for the reformation of cytoskeletal structure. Indentation of a capillary to a cell during microinjection causes influx of calcium ions, as does a typical AFM tip. A nanoneedle, which is a sharpened needle shaped AFM tip of 200 nm in diameter does not cause any influx of calcium ions when it is inserted into a cell. The mechanical stress from the nanoneedle insertion is negligible and its invasiveness is low.
- 公益社団法人 電気化学会の論文
著者
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Nakamura Noriyuki
Research lnstitute for Cell Engineering, Institute of Advanced Industrial Science and Technology
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Nakamura Chikashi
Research Institute For Cell Engineering (rice) National Institute Of Advanced Industrial Science And
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Miyake Jun
Research Institute For Cell Engineering (rice) National Institute Of Advanced Industrial Science And
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NAKAMURA Chikashi
Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Technology
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KAMIISHI Hideki
Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology
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NAKAMURA Noriyuki
Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Technology
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