Comparison of Rhythm Maintenance Effect after Catheter Ablation between Bepridil and Amiodarone for Persistent and Long-Standing Persistent Atrial Fibrillation
スポンサーリンク
概要
- 論文の詳細を見る
<B>Background:</B> Bepridil are frequently administered to patients with persistent or long-standing persistent atrial fibrillation (AF), and the rhythm maintenance effect of bepridil is reported similar to that of amiodarone. However, the availability of bepridil after catheter ablation (CA) is not confirmed. <B>Aim:</B> To evaluate the efficacy of bepridil versus amiodarone in the prevention of AF recurrence after CA. <B>Methods:</B> One hundred and fifteen patients with persistent AF (n=76, male 67, age 60±9) or long-standing persistent AF (n=39, male 19, age 65±10) who underwent medication with amiodarone or bepridil after CA were included. <B>Results:</B> After CA (mean 1.28 procedures), freedom from AF recurrence is higher in persistent AF than long-standing persistent AF (87%, 66/76 vs 69%, 27/39, P=0.014, follow up duration 585±310 days). Long-standing persistent AF accounts for 29% (20/70) in bepridil group and 42% (19/45) in amiodarone group (P=NS). Characteristic parameters (left ventricular ejection fraction, left atrial diameter and structural heart disease) are not different between two groups. There is no significant difference of freedom from AF recurrence between bepridil and amiodarone (81%, 57/70 vs 80%, 36/45, P=NS). <B>Conclusion:</B> The efficacy of bepridil is comparable to that of amiodarone after catheter ablation for persistent and long-standing persistent atrial fibrillation.
著者
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KASENO Kenichi
Division of Cardiology, Gunma Prefectural Cardiovascular Center
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Naito Shigeto
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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Oshima Shigeru
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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Fuke Etsuko
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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Nakamura Kouki
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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Sakamoto Tamotsu
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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Miki Yuko
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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Nakamura Keijirou
Division Of Cardiovascular Medicine Toho University Ohashi Medical Center
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Hayano Mamoru
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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Nishiuchi Suguru
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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Tsukada Naofumi
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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Hayano Mamoru
Division of Cardiology, Gunma Prefectural Cardiovasucular Center
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Kumagai Kouji
Division of Cardiology, Gunma Prefectural Cardiovascular Center
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Miki Yuko
Division of Cardiology, Gunma Prefectural Cardiovasucular Center
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Fuke Etsuko
Division of Cardiology, Gunma Prefectural Cardiovasucular Center
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Naito Shigeto
Division of Cardiology, Gunma Prefectural Cardiovasucular Center
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Kaseno Kenichi
Division of Cardiology, Gunma Prefectural Cardiovasucular Center
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Nishiuchi Suguru
Division of Cardiology, Gunma Prefectural Cardiovasucular Center
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Kumagai Kouji
Division of Cardiology, Gunma Prefectural Cardiovasucular Center
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Sakamoto Tamotsu
Division of Cardiology, Gunma Prefectural Cardiovasucular Center
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Tsukada Naofumi
Division of Cardiology, Gunma Prefectural Cardiovasucular Center
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Nakamura Kouki
Division of Cardiology, Gunma Prefectural Cardiovasucular Center
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