Failure to Raise Blood Pressure During Exercise is a Poor Prognostic Sign in Patients With Hypertrophic Non-Obstructive Cardiomyopathy
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概要
- 論文の詳細を見る
Sudden cardiac death is a well-documented complication of hypertrophic cardiomyopathy and additionally, failure to raise blood pressure (BP) during exercise has been associated with a poor outcome. The present study group comprised 58 patients with hypertrophic non-obstructive cardiomyopathy (HNCM) who were receiving β-blocker therapy. All patients underwent submaximal exercise radionuclide ventriculography (RNVG) to evaluate left ventricular (LV) function at both rest and peak exercise. Patients were divided into 2 groups based on the increase in systolic BP during exercise (ie, group A <30% or group N ≥30% of resting systolic BP) and were involved in long-term follow-up (10.4±4.0 years). Group A comprised 29% of the subjects. Age and workload at peak exercise were similar in the 2 groups. LV end-diastolic dimension was smaller and the interventricular septum was thicker in group A. LV ejection fraction on RNVG was similar in the 2 groups at rest and at peak exercise. During the follow-up period, more patients in group A than group N suffered syncopal attack (29% vs 5%, p<0.05) and cardiac sudden death (24% vs 2%, p<0.05). Patients with HNCM whose BP fails to rise during exercise have a poor prognosis.
- 社団法人日本循環器学会の論文
- 2003-02-20
著者
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SUZUKI tadashi
The Second Department of Internal Medicine,Gunma University School of MedicineThe Second Department
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内藤 滋人
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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Isobe Naoki
Division of Cardiology, Gunma Prefectural Cardiovascular Center
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Adachi Hitoshi
Division of Cardiology, Gunma Prefectural Cardiovascular Center
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Taniguchi Koichi
Division of Cardiology, Gunma Prefectural Cardiovascular Center
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Oshima Shigeru
Division of Cardiology, Gunma Prefectural Cardiovascular Center
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Kubota Sachio
The Second Department Of Internal Medicine Gunma University School Of Medicine
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Naito Shigeto
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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Hoshizaki Hiroshi
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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Oshima Shigeru
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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Kubota Shoichi
Cardiology Divison Yokohama Rosai Hospital
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Ohshima Shigeru
Gunma Prefectural Cardiovascular Center
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Nagaoka Hideki
The Second Department of Internal Medicine, Gunma University School of Medicine
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Suzuki Tadashi
The Second Department Of Internal Medicine Gunma University School Of Medicine
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Suzuki Tadashi
Fujioka General Hospital
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Nagaoka Hideki
Division Of Cardiology Fujioka Manucipal General Hospital
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Taniguchi Koichi
Division Of Cardiology Gunma Prefectural Cardiovascular Center
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