In a Multi-Ethnic Pacemaker Population, Are There Age Related, Gender or Ethnic Differences in Intracardiac Electrogram Amplitudes?

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Background: The impact of age, gender and ethnicity on intracardiac electrogram amplitudes has not been widely studied. With a multi-ethnic population of pacemaker implanted patients in Singapore, we aim to determine if any of the above factors affect intracardiac electrogram amplitudes. Methods: 1813 consecutive patients with pacemakers implanted at National Heart Centre Singapore were studied. Results: Mean age at implant was 70.1±12.3 (SD) years. 54% were females. The 3 major ethnic groups were Chinese 79.6%, Malays 9.5% and Indians 6.6%. Types of pacemakers implanted: VVI/R (46.4%), DDD/R (43.7%), VDD (7.9%), AAI/R (2.0%). All atrial leads were placed at the right atrial appendage. 70% of ventricular leads were placed at the apex with the remainder in the right ventricular mid to high septum. Mean R wave amplitude in mV in females 10.8±4.2 (SD), males 11.1±4.5 (SD). R wave in mV by ethnicity: Chinese 10.9±4.4 (SD), Malays 11.0±3.9 (SD), Indians 11.5±4.4 (SD). Mean P wave amplitude in mV in females 2.9±1.4 (SD), males 3.1±1.5 (SD). P wave in mV by ethnicity: Chinese 3.0±1.5 (SD), Malays 2.9±1.4 (SD). Indians 2.9±1.3 (SD). There were no statistical differences in R or P wave amplitudes by age, gender or ethnic group. Conclusion: In our population, there were no differences in intracardiac electrogram amplitude in the ventricle or atrium between the different ethnic, age and gender groups.