Reverse Left Atrial Remodeling after Radiofrequency Catheter Ablation for Non-Paroxysmal Atrial Fibrillation
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概要
- 論文の詳細を見る
<B>Background & Objectives:</B> Restoration and maintenance of regular rhythm can be achieved by radiofrequency catheter ablation (RFCA) in patients with non-paroxysmal atrial fibrillation (non-PAF). However, it still remains undetermined whether this reversal is accompanied with amelioration of atrial function, which is associated with reduced risk of subsequent thromboembolic events. <B>Methods:</B> We studied 19 consecutive patients (age: 60±12 years) who had received RFCA for non-PAF. Serial changes in left atrial (LA) size and contraction were evaluated with echocardiography at baseline, 2 weeks, 3 months and 12 months after the procedure. <B>Results:</B> Fourteen of 19 patients had recovered and maintained regular rhythm during the follow-up. LA size and biplane volume index reduced over the time (p<0.01 and p<0.01, respectively). Atrial contractibility, assessed by time-velocity integral of atrial wave and atrial filling fraction (p<0.05 and p<0.05, respectively), was improved after the procedure. In addition, atrial compliance, assessed by peak systolic strain of LA inferior and septal wall (p<0.001 and p<0.001, respectively), was also improved over the time. These improvements of LA function were accompanied with that of left ventricular ejection fraction (p<0.001). <B>Conclusion:</B> Restoration and maintenance of regular rhythm achieved by RFCA was associated with reduction in atrial size and volume as well as improvement in contraction. Our findings may encourage usefulness of RFCA for non-PAF, expecting risk of reduction of subsequent thlomboembolic events.
- 日本不整脈学会の論文
著者
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Takenaka Sou
Department Of Cardiology Kurashiki Central Hospital
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Tsurumi Yukio
Department Of Cardiology And Radiology And Department Of Internal Medicine Tokyo Women's Medica
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Ozaki Hiroyuki
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Health Sciences University Of Hokkaido
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Otsuka Masato
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Okayama University
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Nakashima Takashi
Department Of Anatomy Faculty Of Medicine Kyushu University:department Of Anatomy Kyushu Dental Coll
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Takenaka Sou
Department of Cardiology, Yokohama General Hospital
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Tsurumi Yukio
Department of Cardiology, Yokohama General Hospital
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Nakamura Mitsuchika
Department of Cardiology, Yokohama General Hospital
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