Myeloperoxidase Anti-cytoplasmic Antibody Related Crescentic Glomerulonephritis in a Patient with IgG3λ Monoclonal Immunoglobulin Deposition Disease with Membranous Features
スポンサーリンク
概要
- 論文の詳細を見る
A 68-year-old woman showed rapidly progressive glomerulonephritis based on the fact that she had 1+ proteinuria (1.1 g/day), a 3+ occult blood reaction, blood urea nitrogen of 32.4 mg/dL, serum creatinine of 2.96 mg/dL, and myeloperoxidase (MPO)-anti-neutrophil cytoplasmic antibodies (ANCA) at 52 ELISA Unit (normal range: below 10). A renal biopsy demonstrated a bubbling appearance associated with cellular crescent formation with segmental necrosis. Immunofluorescence studies showed granular IgG3λ deposition along the basement membrane and in the mesangial area. This is the first English-language case report describing MPO-ANCA positive crescentic glomerulonephritis in a patient demonstrating monoclonal immunoglobulin deposition disease with mainly membranous features.
著者
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BANNO Shogo
Division of Rheumatology, Department of Internal Medicine and Molecular Science, Nagoya City Univers
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Suzuki Keisuke
Division of Cardiology, Hematology and Endocrinology
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Kitagawa Wataru
Division Of Nephrology And Rheumatology Department Of Internal Medicine Aichi Medical University Sch
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Miura Naoto
Division Of Nephrology And Rheumatology Department Of Internal Medicine Aichi Medical University Sch
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Maeda Sayaka
Division Of Applied Biosciences Graduate School Of Agriculture Kyoto University
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Imai Hirokazu
Division Of Nephrology And Rheumatology Department Of Internal Medicine Aichi Medical University Sch
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Kimura Yukihiro
Division Of Nephrology And Rheumatology Department Of Internal Medicine Aichi Medical University Sch
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Morita Hiroyuki
Division Of Nephrology And Rheumatology Department Of Internal Medicine Aichi Medical University Sch
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Ito Ayano
Division of Nephrology and Rheumatology, Department of Internal Medicine, Aichi Medical University School of Medicine, Japan
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Kitagawa Wataru
Division of Nephrology and Rheumatology, Department of Internal Medicine, Aichi Medical University School of Medicine, Japan
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Suzuki Keisuke
Division of Nephrology and Rheumatology, Department of Internal Medicine, Aichi Medical University School of Medicine, Japan
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Banno Shogo
Division of Nephrology and Rheumatology, Department of Internal Medicine, Aichi Medical University School of Medicine, Japan
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Maeda Sayaka
Division of Nephrology and Rheumatology, Department of Internal Medicine, Aichi Medical University School of Medicine, Japan
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